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Dermatology > SCC/BCC > Flashcards

SCC/BCC Flashcards

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Dermatology Board Prep flashcards
1
Q

What are the traits of Basal Cell CA?

A

Rarely Mets
Local aggresion and tissue destruction
SUN EXPOSURE
Pearly Papules cont prominent dilated SubEpi BV

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2
Q

What is the Tx of BCC?

A 
Excision/Destruction
Small: Cryo/Electrosurg
Topical 
Radiation
Moh's Surgery
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3
Q

What is Moh’s Surgery?

A

Micro Control for lesions in anatomically sensitive areas

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4
Q

What is the pathology of BCC?

A

Nodules attached to the Dermis. Cells line up along nodules. (Along Derm/Epiderm border)

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5
Q

What are the traits of Gorlin Syndrome?

A

AD

Mutation of PTCH Gene on Chromosome 9 (tumor supressor- mutation allows SHH => Cell growth)

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6
Q

What are the Causes of Squamous Cell CA?

A

Caused by UV exposure, HPV, Carcinogens, Chron, ulcers

IMMUNOSUPRESSION

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7
Q

What are the Traits of SCC?

A 
Associated with Actinic Keratosis
Firm Hyperkeratotic Plaque
Can have Erosions and Crusts
Locally Destructive
CAN Mets
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8
Q

SCC in ___________ are most likely to mets.

A

Ear, Lip, Genitalia

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9
Q

What is the Tx of SCC?

A

Excision- Mohs in diff site

Radiation if surgery not sucessful/Feasable

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10
Q

What is the Path of SCC?

A

Proliferation of the Spinous layer of the epidermis

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11
Q

What are the Prognostic facotrs of SCC?

A

Size >4cm
Depth of invasion
Neurotropism
Acantholytic PAttern

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12
Q

What are the Traits of Verrucous CA?

A

Low Grade/ Well Diff variant
Sole of Foot most common
(Sinus Tract?)

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13
Q

What are the traits of Anogenital Verrucous CA?

A

Condyloma Accuminata
HPV related (6 and 11)
Difficult to comtrol

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14
Q

What are the traits of Keratoacanthoma?

A

Rapildy Devt Neoplasm
Mimics SCC
Flesh colored, dome shaped nodules with central keratin filled plug. Crater like

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15
Q

What is the Tx of Keratocanthoma?

A

Surgical Excision

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16
Q

What are trhe Traits of Actinic Keratosis?

A

Squamous Dysplasia (Buildup of Excess keratin)

17
Q

What is the management of AK?

A 
Prev w/ sunscreen!
Cryosurgery
5-FU
Topical Retinoids
Facial Peels
Follow-up w/ monitoring for SCC
18
Q

What are the Traits of Bowenoid Papulosis?

A 
Variant of SCCIS
Anogenital, HPV related
Young SA Adults
Small reddish brown papules
Histo ID to Bowen's
19
Q

WHat are the Traits of Xeroderma Pigmentosum?

A

AR

Sun sensitivity- Sunburn w/ min exposure

20
Q

What is the PAthophys of Xeroderma Pigmentosum?

A

Mult genetic Defects

Can’t repair DNA damage from UV radiation

21
Q

What are the Traits of Merkel Cell CA?

A

Resembles Mets SCC

22
Q

What are the cancers that Most commonly mets to the skin?

A 
Lung
Colon
Melanoma
Oral SCC
Females: BREAST (69%)
23
Q

What is a sister MAry Joseph Nodule?

A

Cancer in the Umbilicus a sign of cancer of the abdomen

24
Q

What are the Traits of Mammary Paget’s Disease?

A

Associated with Mammary Ductal CA

Mistaken for Eczema or psoriasis

25
Q

What are the traits of Atypical Fibroxanthoma?

A

Sun exposed and actinically damaged areas. Head and Neck of elderly
Firm solitary nodule +/- Ulceration

26
Q

What is the Pathology of AFX?

A

Pleomorphic Spindle Cell tumor w/ increased mitotic activity

Dx of Exclusion

27
Q

What are the Types of Kaposi Sarcoma?

A
  • Classic Endemic - Distal ext: Med/Jew pop
  • AIDS Related: HHV8
  • Immunosupression rel
  • African- Sub Saharan

Dermatology (12 decks)

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