Systemic Lupus Erythematosus

Question 1

What is SLE?

Answer 1

Is an inflammatory autoimmune connective tissue disease caused by anti-nuclear antibodies.

Question 2

Presentation + symptoms of SLE?

Answer 2

Fatigue
Weight loss
Joint pain
Myalgia
Fever
Malar rash
Splenomegaly
shortness of breath
hairloss
mouth ulcer

Question 3

Diagnostic criteria for SLE?

Answer 3

P: Photosensitivity
H: Hematological disorder
A: Anti nuclear antibodies
R: Renal disorder
M: Malar rush
A: Arthritis
S: Serositis
U: Ulcers
D: Discord rash

Question 4

Complications of SLE?

Answer 4

Cardiovascular disease
Infection
Anaemia
Pericarditis

Question 5

Treatment of SLE?

Answer 5

First line:
- NSAIDS
- Steroids
- Hydroxychloroquine
- Sun cream