Systemic Diseases with Skin Flashcards
what are skin findings of AL amyloidosis?
macroglossia
pinch purpura
nodules and plaques in periorbital region
what disease has pinch purpura with macroglossia?
AL amyloidosis
what type of granulomas are in sarcoidosis?
non caseating
how does sarcoid appear on skin?
symmetric red/brown papules and plaques
what is lofgrens syndrome?
sarcoidosis with erythema nodosum, hilar lymphadenopathy fever and polyarthritis
what do sarcoidosis skin lesions have a preference for?
tattoos and scars
a patient with history of diabetes presenting with reddish brown plaques on her shins may have what issue?
necrobiosis lipoidica
what is necrobiosis lipoidica?
necrotizing skin condition affiliated with diabetes
what do lesions look like with necrobiosis lipoidica?
reddish brown plaques on shins
what happens to sensation around plaques from necrobiosis lipoidica?
loss of sensation over the plaques
what is first line treatment for necrbiosis lipoidica?
topical steroids
what is Sweets Syndrome other name?
acute febrile neutrophilic dermatosis
what happens in Sweets syndrome?
fever with abrupt onset of erythematous plaques
where do plaques commonly occur in sweets syndrome?
head neck and upper extremities
what will labs show with Sweets syndrome?
elevated WBC with high neutros
what is a common trigger for Sweets syndrome? what is another trigger to be aware of?
infections
be aware of malignancies and chronic inflamm disorder
what is treatment for Sweets disorder?
treat underlying infection or disease and give systemic steroids
how does erythema nodosum appear on skin?
tender nodules on anterior lower legs without ulcerations
does eryhtema nodosum have ulcerations?
NO
50% of erythema nodosum is idiopathic…but other 50% has a few common triggers..what are they?
post strep infection OCPs Abx pregnancy chronic inflamm disorders
how to treat erythema nodosum
NSAIDs
what are systemic symptoms of erythema nodosum?
arthritis
fever
arthralgia
malaise
what is skin manifestation that is associated with ESRD?
calcific uremic arteriopathy
what does skin look like in calcific uremic arteriopathy?
violaceous subcutaneous nodules and plaques
is calcific uremic arteriopathy painful on skin?
you betcha
what can calcific uremic arteriopathy lead to on skin?
ulcers
where do you find the nodule and plaques from calcific uremic arteriopathy?
lower extremities and trunk
what does biopsy show in calcific uremic arteriopathy?
arteriolar calcification
what do you do to help calcific uremic arteriopathy?
surgical debridement
