Systemic Diseases with Skin

Question 1

what are skin findings of AL amyloidosis?

Answer 1

macroglossia
pinch purpura
nodules and plaques in periorbital region

Question 2

what disease has pinch purpura with macroglossia?

Answer 2

AL amyloidosis

Question 3

what type of granulomas are in sarcoidosis?

Answer 3

non caseating

Question 4

how does sarcoid appear on skin?

Answer 4

symmetric red/brown papules and plaques

Question 5

what is lofgrens syndrome?

Answer 5

sarcoidosis with erythema nodosum, hilar lymphadenopathy fever and polyarthritis

Question 6

what do sarcoidosis skin lesions have a preference for?

Answer 6

tattoos and scars

Question 7

a patient with history of diabetes presenting with reddish brown plaques on her shins may have what issue?

Answer 7

necrobiosis lipoidica

Question 8

what is necrobiosis lipoidica?

Answer 8

necrotizing skin condition affiliated with diabetes

Question 9

what do lesions look like with necrobiosis lipoidica?

Answer 9

reddish brown plaques on shins

Question 10

what happens to sensation around plaques from necrobiosis lipoidica?

Answer 10

loss of sensation over the plaques

Question 11

what is first line treatment for necrbiosis lipoidica?

Answer 11

topical steroids

Question 12

what is Sweets Syndrome other name?

Answer 12

acute febrile neutrophilic dermatosis

Question 13

what happens in Sweets syndrome?

Answer 13

fever with abrupt onset of erythematous plaques

Question 14

where do plaques commonly occur in sweets syndrome?

Answer 14

head neck and upper extremities

Question 15

what will labs show with Sweets syndrome?

Answer 15

elevated WBC with high neutros

Question 16

what is a common trigger for Sweets syndrome? what is another trigger to be aware of?

Answer 16

infections

be aware of malignancies and chronic inflamm disorder

Question 17

what is treatment for Sweets disorder?

Answer 17

treat underlying infection or disease and give systemic steroids

Question 18

how does erythema nodosum appear on skin?

Answer 18

tender nodules on anterior lower legs without ulcerations

Question 19

does eryhtema nodosum have ulcerations?

Answer 19

NO

Question 20

50% of erythema nodosum is idiopathic…but other 50% has a few common triggers..what are they?

Answer 20

post strep infection
OCPs
Abx
pregnancy 
chronic inflamm disorders

Question 21

how to treat erythema nodosum

Answer 21

NSAIDs

Question 22

what are systemic symptoms of erythema nodosum?

Answer 22

arthritis
fever
arthralgia
malaise

Question 23

what is skin manifestation that is associated with ESRD?

Answer 23

calcific uremic arteriopathy

Question 24

what does skin look like in calcific uremic arteriopathy?

Answer 24

violaceous subcutaneous nodules and plaques

Question 25

is calcific uremic arteriopathy painful on skin?

Answer 25

you betcha

Question 26

what can calcific uremic arteriopathy lead to on skin?

Answer 26

ulcers

Question 27

where do you find the nodule and plaques from calcific uremic arteriopathy?

Answer 27

lower extremities and trunk

Question 28

what does biopsy show in calcific uremic arteriopathy?

Answer 28

arteriolar calcification

Question 29

what do you do to help calcific uremic arteriopathy?

Answer 29

surgical debridement