Psoriasis Flashcards
what percent of psoriasis is genetic?
33
name the five types of psoriasis
plaque inverse/flexure guttate aryhtrodermic pustular
what often precedes guttate psoriasis?
strep pharyngitis
describe the lesions in guttate psoriasis and location
acute onset of raindrop sized lesions on trunk and extremities
where do inverse/flexure psoriasis plaques occur?
axilla
groin
inframammary region and skin fold
what do inverse/flexure psoriasis plaques look like?
large erythematous plaques that may lack scales
where does pustular psoriasis occur?
can be anywhere on the body
what often precedes pustular psoriasis?
corticosteroid withdraw
what do pustular psoriasis lesions look like?
psoriatic lesions that are erythematous and have pustules on them
what is palmoplantar psoriasis?
psoriasis on the foot…often confused with athletes foot
what two types of psoriasis commonly cause palmoplantar?
plaque or pustular
describe psoriatic erythroderma
entire skin surface turns bright red
what two things is psoriatic erythroderma associated with?
fever and chills
describe plaque psoriasis lesions
well demarcated plaques with overlying silvery scale and underlying erythema
is plaque psoriasis usually symmetric or asymmetric?
symmetric
what is the Koebner phenomenon? what is it associated with?
associated with psoriasis…is lesions induces by trauma
describe the pathogenesis of plaque psoriasis
cytokines from immune cells trigger hyperproliferation of skin…leading to thick scaley skin
name four things patients with psoriasis have an increased risk for
metabolic syndromes
deprssion
obesity
alc or tobacco
name the six common locations for psoriasis to appear
scalp ears elbows knees umbilicus nails gluteal cleft trauma sites
what is psoriatic onychodystrophy?
nail psoriasis
how often are nails involved in psoriasis?
bout 50%
what does psoriatic onychodystrophy put you at higher risk for with psoriasis?
psoriatic arthritis
does psoriatic arthritis have antibodies to test for?
no it is seronegative
what joints are most common in psoriatic arthritis?
distal interphalangeal joints
what is first line treatment for localized plaque psoriasis?
high potency topical steroid
what should you never give for psoriasis? why?
oral steroids cause they can cause a psoriasis flare
name the two systemic medications that are not biologics that you can give for psoriasis
methotrexate
cyclosporine
what type of biologics can you give for psoriasis?
TNFa inhibs like infliximab and adlimumab and etanercept
what is a treatment for systemic psoriasis that is not medication?
UV light therapy
