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Derm > Cutaneous ImmunoMicro > Flashcards

Cutaneous ImmunoMicro Flashcards

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Dermatology Board Prep flashcards
1
Q

what are the two innate immuno cells in the skin?

A

dendritic and mast

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2
Q

what is the adaptive cell in the skin?

A

T cell

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3
Q

what type of bug is in dry skin?

A

gram pos

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4
Q

what type of bug is in wet skin?

A

gram neg

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5
Q

where do most bugs reside in the skin?

A

stratum corneum

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6
Q

what is the main aerobic bug in skin?

A

staph epidermidis

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7
Q

what bug is common on skin of people with atopic dermatitis?

A

staph aureus

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8
Q

what is the bug that causes acne?

A

propionibacterium acnes

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9
Q

what skin cell actually has immune function?

A

keratinocytes

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10
Q

what are the two antimicrobial peptides to know for the skin?

A

B defensin and LL37

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11
Q

what do B defensins and LL37 antimicrobial peptides do to skin bacteria?

A

they can aggregate and form pores to help kill the bacteria

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12
Q

what can staph epidermidis do to help immune response at skin?

A

it educates the CD8 cells and leads to induction of IL17 that leads to keratinocytes enhancing their barrier function

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13
Q

name the two common bacteria that cause skin infections

A

staph a

strep pyogenes

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14
Q

name the two fungi that cause skin infections

A

candida and dermatophytes

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15
Q

name the four virus classes that cause skin infections

A

childhood viruses
HPV
VZV
molluscum contagiosum

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16
Q

what can staph a and strep pyo make that lead to toxic shock syndrome of skin?

A

superantigens

17
Q

what is the bacteria that infects with RMSF?

A

rickettsia ricketsii

18
Q

what is the bug that causes syphillis

A

treponema pallidum

19
Q

what three areas do dermatophytes infect comonly?

A

skin hair and nails

20
Q

what are the three virulence factors in fungi?

A

proteases, keratinases, lipases

21
Q

name the two enveloped RNA viruses that have skin involvement

A

measles and rubella

22
Q

name the non enveloped RNA virus that has skin manifestation

A

parvovirus B19`

23
Q

name the enveloped DNA viruses that have skin manifestations

A

HHV 6 and 7

24
Q

how does zoster or shingles appear on a rash/

A

erthyematous and follows a dermatome

25
Q

why does zoster/shingles follow a dermatome?

A

because it hangs out in a dorsal root ganglia following chicken pox

Derm (22 decks)

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