Systemic Diseases

Question 1

Takayasu

Answer 1

Women of childbearing age
Large vessel vasculitis
Stenosis of aneurysms of aorta / branches
Subclavian stenosis
HTN, TIA/CVA, myocarditis, vasculitis

Question 2

Relapsing polychondritis

Answer 2

Aortic or mitral valve disease, AR

Question 3

Hemochromatosis

Answer 3

Normall wall thickness
DCM, hepatic dz, DM, tanned skin
Arrhythmias, conduction abnormalities
Restrictive filling

Question 4

Eosinophilic heart disease

Answer 4

Apical thrombi, endocardial thickening
Restrictive
Leaflet entrapment, MV > TV, MR and TR
Biatrial enlargement

Question 5

Carcinoid

Answer 5

GI tumors

Usually right sided valves, thickening and reduced mobility

Question 6

Drug-induced valvular disease

Answer 6

ErgotsLooks like rheumatic

Question 7

Vitamin deficiency associated with cardiomyopathy

Answer 7

Selenium
Thiamine
Carnitine

Question 8

Thiamine deficiency

Answer 8

High output heart failure

Question 9

Selenium deficiency

Answer 9

TPN

Cardiac enlargement and systolic heart failure

Question 10

Carnitidine deficiency

Answer 10

TPN or genetic defect

Systolic dysfunction

Question 11

Chagas echo

Answer 11

BIventricular enlargement
Ventricular wall thinning
Apical aneurysm
Mural thrombi

Question 12

Friderich ataxia

Answer 12

Autosomall recessive
Concentric hypertrophy mimicking HCM
Globally decreased EF, LV-end diastolic diameter

Question 13

GPA echo

Answer 13

Small vessel vasculitis

Regional WMA not in typical coronary distribution

Question 14

Amyloid echo

Answer 14

LV wall thickening
DD
Progression to restrictive CMY with non dilated or small cavity

Question 15

Sarcoid echo

Answer 15

LV systolic dysfunction
RWMA in non-coronary distribution 
Abnormal wall thickness
Perfusion defects in anteroseptal and apical regions
AV block

Question 16

Risk factors for peripartum CMY

Answer 16

Age > 30
Multiparity
African descent
Pregnancy with multiple fetuses
Preeclampsia / eclampsia
Postpartum hypertension
Oral tocolytics

Question 17

Cardiac manifestations of HIV

Answer 17

Pericardial effusion (most common)
DCM
Primary pulmonary hypertension
Kaposi sarcoma
CAD

Question 18

Pheochromocytoma

Answer 18

HTN
Reversible WMAs
DCM

Question 19

Cushing syndrome

Answer 19

Excess glucocorticoid

Moderate chronic diastolic HTN

Question 20

Rheumatoid arthritis

Answer 20

CAD, diastolic dysfunction

Question 21

Takotsubo

Answer 21

Transient apical and mid ventricular WMAs

Dynamic LVOT obstruction, RV apical dysfunction may occur

Question 22

Scleroderma

Answer 22

Pericardial effusion
Systemic and pulmonary hypertension
May have systolic / diastolic dysfunction

Question 23

Libman Sacks endocarditis

Answer 23

SLE

Small verrucous valvular lesions, usually MV, ventricular aspect

Question 24

Fabry disease

Answer 24

Angiokeratomas, neuropathic pain, teleangiectasias, heat intolerance, GI symptoms, renal manifestations
Concentric LV hypertrophy
Myocardial dysfunction 
Aortic and mitral valve abn
Conduction abnormality

Question 25

Tuberous sclerosis

Answer 25

Neurocutnaeous disorder, hamartomas

Rhabdomyoma - kids, benign, multiple, ventricular walls or AV valves

Question 26

Marfan syndrome

Answer 26

Pear shaped dilatation of aortic root

Question 27

Extra-adrenal paraganglioma

Answer 27

Headache, sweating, tachycardia

Like pheochromocytoma

Question 28

Carney syndrome

Answer 28

Autosomal dominant
Myxoma, schwannoma, endocrine tumors
Pigmentation abnormalities