Systemic disease Flashcards
cerebral salt wasting vs SIADH
in SIADH, the central venous pressure may be high from free water retention
rate that is okay to correct hyponatremia?
12 mEq/L/day
mainstay of treatment for SIADH
water restriction <800mL/day
normal serum osmolality?
270
urine Na in SIADH vs DI?
SIADH UNa>20, DI UNa<20
hypercalcemia causes what probs at what level?
> 12: Fatigue depression
14: stupor, weakness, coma
GI effects
What are Trousseau and Chvostek?
Hypocalcemia signs:
Trousseau: BP cuff
Chvostek: face tapping
which magnesium gives you depressed reflexes?
hypermagnesium
consider what dx? cognitive impairment, variable psych sx, involuntary mvmts, sz, myoclonus, opsoclonus, chorea, stroke-like episodes, myelopathy?
Dx and labs and Tx
Hashimoto’s encephalopathy - check antimicrosomal/antithyroglobulin antibodies,antithyroid peroxidase, TSH receptor blocking Abs. Responds very well to steroids
micro vs macro pituitary adenomas
> 1cm macro
most common pituitary adenoma
lactrotroph (prolactin)
treatment of pituitary apoplexy
medical and surgical emergency
IV steroids + surgical decompression
vitamin deficiency that can mimic Friedreich ataxia: sensory ataxia, areflexia, neuropathy
vit E deficiency
familial fat malabsorption disease that can lead to fat soluble vitamin deficiency?
Abetalipoproteinemia (Bassen-Kornzweig)
ferritin level to treat
<50
