Sleep Flashcards
Purpose of Pittsburgh sleep quality inventory
overall sleep functioning questionnaire
Purpose of Berlin and Stop BANG questionnaires?
OSA sx checklist
Epworth questionnaire used for what?
What is the scale cut offs
subjective sleepiness,
scale > 10 sleepy; >18 very sleepy
Name the four sleep phases
Stage R (REM)
Stage N1 (drowsy twilight: stage 1)
Stage N2: light NREM
Stage N3/4: deep slow wave NREM sleep
What happens to REM sleep and slow wave stage N3 sleep throughout the night?
Increased REM time, decreased N3
BMI with increased risk of OSA?
BMI > 30 (mild obesity)
biochemical issue in narcolepsy
Genetic finding in narcolepsy/cataplexy?
decreased hypocretin (orexin) genetics: HLA-DQB1-0602 (85% n/c pts are pos, so are 20% controls)
major sx of narcolepsy is ____ NOT ____
excessive daytime sleepiness NOT sleep attacks
what is cataplexy?
episodic weakness / loss of tone esp when excited / laughing
Abnormal levels on multiple sleep latency test for narcolepsy?
- < 8 min to fall asleep is pathological sleepiness
2. SOREM: number of REM onset sleep periods > 2 (of 5 naps)
What is the maintenance of wakefulness test used for?
Test of treatment effectiveness in narcolepsy: 40 min staying awake w/ eyes closed in chair x 4
Drugs for narcolepsy? (3)
Armodafinil (long acting), Modafinil, stimulants
Tx for cataplexy (2)
SSRI or Sodium oxybate
What is Kleine-Levin syndrome?
hypersomnolence disorder with hypersexuality, intermittent/periodic
What terrible disease can be assoc w/insomnia?
fatal familial insomnia: prion dz