neuro-ophtho / otology Flashcards
asymmetry or loss of OKN is what?
parietal lobe lesion
OKN uses same side of brain to pursue and to correct the saccade to catch the next stripe
pursuit vs saccade brain regions
saccades: catch it with contralateral frontal lobe
pursuit: ipsilateral parietal temporal lobe
lesion of fasicle and superior cerebellar peduncle causes what and name of lesion
nothnagel: ipsilat CN 3 palsy and cerebellar ataxia
what will a third nerve nucleus lesion give you?
right nuclear cn3: loss of CN3 on third side AND gets levator palpebrae nucleus which is single, so both eyes get ptosis, and superior rectus on opposite side will also be affected.
6th and 7th nerve palsy with contralat hemiparesis
millard gubler
ipsilat gaze palsy, 5, 7, and horner’s
foville’s
where is the vertical gaze center locted
near midbrain / CN III nucleus
where is the horizontal gaze center in brain
in pons, near CN VI nucleus
area of brain responsible for saccades vs pursuit
saccades: contralat frontal lobe (jerk correction / fast phase)
pursuit: ipsilat parieto/occipital lobe (slow phase)
lesion is where when you get an isolated CN 6 and a horner’s
small cavernous sinus lesion near the CN 6/ICA w/ sympathetics sparing the wall of the sinus where the other CNs are
how do you differentiate a supranuclear vs brainstem gaze palsy
if doll’s eye can move eyes, the lesion is supranuclear
2 main possible causes of a vertical gaze palsy
- dorsal midbrain / parinaud syndrome
2. PSP (PD + syndrome)
4 components of a dorsal midbrain lesion syndrome?
- vertical gaze palsy
- OKN downgoing, get a convergence/retraction nystagmus
- Pupil: convergence response but no light response: light/near dissoc and pupils are BIG
- lid retraction
If you get a vertical gaze palsy and convergence retraction nystagmus, but positive doll’s eye movement, what is diagnosis?
PSP
bilateral failure of adduction with horizontal gaze with fully abducted other eye beating?
INO
complete failure to look right, and when looking left, the right eye doesn’t adduct
1.5 syndrome gets the pPRF and CN6 nuclear complex and the MLF
what are the three components of the SNS pathway for pupil dilation
1st order: in brainstem
2nd order: C8-T2 at ciliospinal center of Budge to apex of lung and around subclavian artery to superior cervical ganglion
3rd order: along the ICA (in part with CNVI in the cavernous sinusO)
what is Hutchinson sign with zoster lesions?
lesion of tip of nose: may indicate involvement of nasociliary branch and means eye is at risk
involvement of mild ptosis with upper and lower lid involved
mullers / SNS
what does aproclonidine drop do
Horners tests that would dilate the pupil in a Horners even when cocaine would not.
what does hydroxyamphetamine / paradrine drop do
horners: will distinguish between 1/2 or 3rd order; dilates only in 1/2nd not benign third
only type of horners usually benign unless what
3rd order, unless with pain, in which case worry about carotid dissection
what do you get if you have a Horners and heterochromia
congenital issues b/c SNS is also responsible for giving color or iris
vermiform eye movements with light
this pupil is very sensitive to what drop
tonic pupil
very sensitive to pilocarbine
what is Adie’s
tonic pupil plus loss of DTRs
argyll robertson pupil vs parinaud pupils and adie’s pupils
argyll robertson has small pupils.
parinauds and adies have large pupils
all accomodate but don’t really react to light well
think of what with bilateral central visual field defects (3 examples)
toxic or genetic
- ethambutol
- Lebers
- NMO/Devics
micro vs macroadenoma
10mm
when someone is complaining on intermittent diplopia or blindness without any CN palsy, think what?
could be a loss of vision convergence due to bitemporal blind fields overlapping OR loss of intermittent phoria/drift
Think pituitary tumor
bow tie atrophy of fundi seen in what?
bitemporal visual field lesions w/ pituitary tumors
where is lesion if you get a large central visual field defect in one eye and a upper temporal field cut (pie in sky) in other eye?
large optic nerve lesion that catches the looping fibers: junctional scotoma
lesion that creates visual field defects with wedges / wisps of spared areas?
LGN lesion: onion / laminar sparing of layers
pie in the sky field defect is lesion where?
inferior temporal optic tract/radiations lesion
increased congruity in visual field defects r/l eyes with lesions where
more posterior leads to more congruity
where is the lesion if you get a large homonymous hemianopsia but with an area of far temporal field spared?
occipital lobe
far temporal and macular sparing hemianopsia- where is lesion?
occipital lobe