synthesis of fatty acids Flashcards
The end product of de novo synthesis is
palmitic acid
excessive carbohydrates and proteins can be converted to fatty acids and stored as TAGs by the process of
de novo synthesis
De novo synthesis primarily takes places in what three places
liver, lactating mammary glands and adipose tissue
in de novo synthesis citrate is transferred from the mitochondria to the cytosol to be resynthesized to
Acetyl Coa
High levels of ATP ______de novo synthesis
enhance
The rate limiting enzyme of de novo synthesis is?
acetyl Coa carboxylase
________activates acetyl Coa carboxylase causing dimers to be polymerized
citrate
________inactivates acetyl Coa carboxylase
long chain fatty acids
acetyl Coa carboxylase adds ______ to _______ resulting in
acetyl coA
CO2
Malonyl CoA
______ and ________regulates acetyl Coa carboxylase to stop
glucagon
epinephrine
fasting
_________regulates acetyl Coa carboxylase to go
insulin
fed state
Fatty acid synthase is an enzyme that _____ resulting in______as the end product
adds carbon molecules to the growing fatty acid chain resulting in palmitate as the end product
The metabolic interrelationship between glucose metabolism and palmitate synthesis is
NADPH from the pentose phosphate pathway
