Phospholipids Flashcards

1
Q

Phospholipids are not amphipathic. T/F

A

False

Phospholipids are amphipathic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Phospholipids are composed of?

A

alcohol attached by phosphodiester bridge to diacylglycerol or sphingosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

phospholipids are polar or non polar?

A

polar

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

phospholipids are _____ ____ _____ and play a role in generation of ______ ____ _____.

A

structural components of membranes

lipid signaling molecules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

__________is important in the formation of myelin in nerve fibers.

A

sphingomyelin

sphingosine backbone instead of glycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Dipalmitoyl-phosphatidylcholine DPPC is important for what?

A

major lipid component for surfactant synthesized and secreted by type 2 pneumocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

an important phospholipid that contains arachidonic acid is?

A

phosphatidylinositol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

arachidonic acid is important for?

A

prostanoid synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What pathway activates phosphatidylinositol, IP3, DAG

A

Gq, A1, epi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

important for signal cascade

A

phosphatidylinositol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

phosphatidylinositol plays an important role in membrane

A

protein anchoring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

phosphatidylinositol plays an important role in membrane protein anchoring of _____ and ______

A
  • alkaline phosphatase (digestive enzyme) in small intestine
  • acetylcholine esterase
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

phosphatidylinositol can be cleaved by______to release ______

A

phospholipase C

diacylglycerol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Phospholipid A2 is inhibited by

A

glucocorticoids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

phospholipid A2 acts on phosphatidylinositol releasing_____

A

arachidonic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Membrane bound phospholipase C is activated by pip2 and plays an important role in_____

A

producing second messengers

17
Q

Phosphatidylinositol can be cleaved from its anchor by ______ releasing _____

A

PLC

diacylglycerol