Cholesterol

Question 1

cholesterol is a precursor of 3

Answer 1

bile salts
steroid hormones
vitamin D

Question 2

the major organ of cholesterol metabolism

Answer 2

liver

Question 3

cholesterol is very hydrophobic and composed of

Answer 3

four fused hydrocarbon rings and steroid nucleus

Question 4

cholesterol is synthesized where?

4

Answer 4

liver
intestine
adrenal cortex
gonads make largest contribution

Question 5

Cholesterol is synthesized by

Answer 5

HMG CoA reductase (rate limiting by cholesterol levels)

acetyl coa to hmg coa
HMG CoA reductase converts hmg coa to mevalonate

Question 6

insulin hormonally controls cholesterol synthesize by?

Answer 6

up regulation of HMG CoA reductase

Question 7

how is cholesterol sterol nucleus eliminated?

Answer 7

converted to bile salts and acids
excreted in feces

secretion of cholesterol in bile

Question 8

bile salts are conjugated with either

Answer 8

glycine or taurine