Synaptic Transmission & Neural Integration Flashcards
What is a synapse?
functional association of a neuron with something else
What are the two types of synapses?
electrical & chemical
What do electrical synapses not have that chemical synapses do?
neurotransmitters
What links two neurons together?
gap junction
Synaptic Communication
- action potential
- voltage gated Ca2+ channels open, Ca2+ entry
- exocytosis
- neurotransmitter diffuses across cleft & binds to receptor
- response in cell
- neurotransmitter is removed
Are ligand-gated receptors considered fast or slow?
fast
Are GPCR receptors considered fast or slow?
slow
What is the most common CNS neurotransmitter for EPSP?
glutamate
What is the most common CNS neurotransmitter for IPSP?
GABA
What is EPSP responsible for?
depolarization
What is IPSP responsible for?
hyperpolarization
Which postsynaptic potential (PSP) is more likely to produce an action potential?
EPSP
What are the two graded potentials?
EPSP & IPSP
What are the two types of summation?
temporal & spatial
Temporal summation
sum of one synapse through time; EPSP is generated rapidly