Synaptic Transmission II Flashcards
Number of vesicles expected to participate in exocytosis
PN
Probability that a vesicle will under exocytosis
P
Number of vesicles available for exocytosis
N
Probability that a vesicle will undergo exocytosis in absence of what
Calcium
Post synaptic response to the transmitter ejected from a single vesicle
Quintal size
Number of vesicles released per impulse
Quantum content
Bacterial protease arising from infection or ingestion
Botulinum Toxin
What enters peripheral motor neurons and cleaves synaptobrevin, disrupting acetylcholine release resulting in weakness
Botulinum Toxin
Bacterial protease arising from infection
Tetanus Toxin
What enters peripheral motor neurons and undergoes retrograde transport, cleaves synaptobrevin and disrupts glycine release causing muscle spasms
Tetanus Toxin
What drugs block voltage-gated Ca2+ channels
Aminoglycoside Antibiotics
What drug blocks voltage-gated K+ channels increasing duration of action potential by increasing influx of Ca2+
4-Aminopyridine
High frequency stimulation by one presynaptic neuron
Temporal
Simultaneous stimulation by several presynaptic neurons
Spatial summation
Fear potentiation of acoustic startle b/c amygdala and nucleus of lateral lemniscus converge
Spatial summation