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NB Exam 1 > Paroxysms And Synaptic Plasticity > Flashcards

Paroxysms And Synaptic Plasticity Flashcards

1
Q

What are memories stored as

A

Engrams

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2
Q

What are acquired pathological deficits of memory

A

Amnesia’s

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3
Q

Amnesia’s can be a result from what

A

Failure to produce engrams

Losses of engrams

Failure in accessing engrams

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4
Q

High frequency stimulation at hippocampal synapses

A

Long term potentiation

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5
Q

Low frequency stimulation at hippocampal synapses

A

Long term depression

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6
Q

High frequency stimulation

A

Large Ca2+ influx, receptors inserted

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7
Q

Low frequency stimulation

A

Small Ca2+ influx, receptors removed

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8
Q

Sudden onset bursts of neuronal activity causing seizures

A

Paroxysms

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9
Q

Pathological synchronization of neuronal activity

A

Seizures

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10
Q

Seizures lasting beyond 5 mins causing excitotoxicity (cerebral damage)

A

Status epilepticus

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11
Q

Motor is manifestations of seizure

A

Convulsion

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12
Q

Chronically heightened susceptibility to seizures

A

Epilepsy

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13
Q

Transformation of non-epileptic brain into epileptic brain

A

Epileptogenesus

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14
Q

Type of seizure that is bilateralized and consciousness throughout

A

Primary generalized

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15
Q

Type of seizure that is bilaterized and arises from a partial seizure and consciousness lost at transition from partial to generalized

A

Secondary generalized

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16
Q

Type of seizure that is localized, awareness may be preserved (simple) or disturbed (complex)

A

Focal (partial)

17
Q

Characteristics of infantile spasms

A

Hypsarrhythmia

18
Q

Characteristics of absence seizures

A

Spikes and waves

19
Q

Select Antiseizure Strategies

A

Na+ channel blocker

Ca2+ channel blocker

GABA agonists

20
Q

Two types antiseizures of drugs that are GABA agonists

A

Benzodiazepines

Barbiturates

21
Q

Antiseizure drug that acts as a Na+ and Ca2+ channel blockers

A

Valproate

NB Exam 1 (13 decks)

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