Stimulated Excitable Cells Flashcards

1
Q

Ion channels react to stimuli, increasing or decreasing ionic flux

A

Signal transduction

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2
Q

Receptor and postsynaptic potentials grow smaller with distance from initiation site

A

Decremental potential

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3
Q

Distance over which a electrical potential decays

A

Length constant

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4
Q

What does greater length constant indicate

A

Lesser decrement

Lower intracellular resistance

Greater membrane resistance

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5
Q

Which area of the axon is populated by voltage-gated sodium channels

A

Impulse Initiation zone

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6
Q

Ionic basis of action potentials

A

Na+ channels open then inactivate

K+ channels wait, open and inactive slowly

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7
Q

Inactivation ball plugs channel

A

Channel remains inactive until voltage resets (absolute or relative refractory)

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8
Q

How is the distribution of voltage-gated channels on unmyelinted axons

A

Sparse distribution

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9
Q

How is voltage-gated distribution on myelinated axons

A

Dense (nodes of Ranvier)

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10
Q

High intracellular resistance

A

Short length constant

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11
Q

Low intracellular resistance

A

Long length constant

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12
Q

Drug that blocks voltage-gated Na+ channels

A

Lidocaine

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