synapses Flashcards
1
Q
what happens at a synapse
A
- AP depolarises terminal
- Ca2+ chan open
- influx of Ca2+
- vesicles fuse w PSM
- NT released by exocytosis
- NT diffuses across SC
- binds to receptor
- post synaptic response
2
Q
what do electrical, mechanical or chemical stimuli do to transmembrane ion distribution
A
changes it
3
Q
local response
A
- non propagated
- at dendrites and cell body
4
Q
propagated disturbance
A
- AP
- all or nothing
- strength does not diminish
5
Q
what NT is used in EPSPs
A
ACh
6
Q
how many molecules of ACh bind at NMJ
A
2
7
Q
NT for IPSPS
A
GABA, Cl- enters which makes cell more -ve. local hyperpolarisation inside
8
Q
spatial summation
A
2 EPSPs on adjacent membranes
9
Q
temporal summation
A
2 EPSPS close in time
10
Q
what are classed as aminoacid NTs
A
Glycine and GABA
11
Q
what are classed as classical NTs
A
ACh and NA
12
Q
what are classed as peptide NTs
A
TRH and Substance P
13
Q
what makes ACh
A
acetyl CoA and Choline
14
Q
2 types of excitable cells
A
muscle and nerve
15
Q
excitable cells
A
transmit electrochemical signals along their membranes by moving charged ions across the cell membrane
