Sympatholytic (Adrenergic Agonist) Flashcards
Non-Selective Alpha Blockers
- Phenoxybenzamine - irreversible
- Phentolamine - reversible
Selective Alpha-Blockers
Alpha 1
Prazosin
Doxazosin
Terazosin
Silodosin
Tamsulosin
Alfuzosin
Alpha 2
Rauwolscine
Yohimbine
Non-Selective Beta-adrenoceptor Antagonist
Propranolol
Timolol
Pindolol
Nadolol
Selective Beta-adrenoceptor Antagonist
Bisoprolol
Betaxolol
Esmolol
Atenolol, Acebutolol
Metoprolol
Treatment of Pheochromocytoma/Carcinoid Syndrome
Phenoxybenzamine
Phentolamine reverses effect of
Epinephrine
Alpha-blockers effect
First dose phenomenon
Orthostatic/ Postural Hypotension
Reflex tachycardia
Dizziness
Headache
Nasal congestion
Treatment of Hypertension and BPH
Prazosin, Doxazosin, Terazosin
Effects: Vasodilation
Treatment of BPH only
Silodosin
Tamsulosin
Alfuzosin
Treatment of Hypertension without asthma
Non-Selective β-Blockers (NSTP)
Propranolol
Timolol
Pindolol
Nadolol
Treatment pf Hypertension with Asthma
Metoprolol
Atenolol
Esmolol
MAE HYPERTENSIVE ASTHMATIC
Most cardioselective beta-blocker
Nebivolol
Uses of Nebivolol
increases NO or EDRF11
1st line for HTN in px with hx of MI
Management of Angina Pectoris
management of stable heart failure
Clinical Uses of Beta-blockers
Mx of Angina Pectoris
Mx of arrhythmia
Mx of sympathetic symptoms of hyperthyroidism Mx of Glaucoma
Mx of stable CHF(Congestive Heart Failure)
Mx hypertension
Prophylaxis for Migraine
Has the shortest duration of action (t ½ = 10 minutes)
Esmolol
