Sweep 4

Question 1

• “persister cells”

Answer 1

that are alive but metabolically inactive survive and re-
populate biofilm (“viable but non-cultivable”)

Question 2

bisphosphonate therapy

Answer 2

(anti-osteoclastic drug).

Question 3

lactate required by

Answer 3

Veillonella

Question 4

Streptococcus salivarius produces ======= that inhibitis ————

Answer 4

enocin

S. pyogenes

Question 5

Cerebrospinal fluid (CSF) shunts

Answer 5

Ventriculo-peritoneal (VP)
• Doesnotinvolvevascular structures, so low bacteremia
• Skin,notoralbacteria
• Highrateofinfection
• Prophylaxisnotrecommended Ventriculo-atrial (VA)
• AHA2003noevidencethat microorganisms associated with dental procedures cause infection of these shunts

Question 6

Critical Items must be

Answer 6

sterilized

Question 7

Semicritical Items require

Answer 7

High or intermediate-level disinfection

Question 8

Quarternary alcohol - Caviwipes

Answer 8

Cleaner & intermediate level disinfectant for semicritical items (in contact with intact mucous membranes)

Question 9

Phenols and derivatives

Answer 9

Intermediate level disinfection

Question 10

Aspartame

Answer 10

• not safe in phenylketonuria

* not heat stable, so not used in baked goods

Question 11

Crystal growth does not occur due to salivary pellicle proteins that coat the enamel surface

Answer 11

• tyrosine-rich peptides
• statherin
• proline-rich proteins

Question 12

F- binds to sites that would normally bind OH- and

Answer 12

inhibits enzymes and regulatory proteins

Question 13

Fluoride can inhibit ———- (enzyme in glycolytic pathway to lactate production) well documented

Answer 13

enolase

Question 14

a. Lactic acid- produced by metabolism of sugars by

Answer 14

streptococci

Question 15

• S. mutans- primary caries pathogen, gram+ cocci, facultative
advantages to host:

Answer 15

o Advantage to host- low levels of lactate protective against pathogens