Sweep 3 Flashcards
Necrotizing Ulcerative Periodontitis: involvement of palatal mucosa leads to
necrotizing stomatitis
Incidence of LAP is ——– people at risk (14- to 15-year old)
1.3/1000
Primary herpetic gingivostomatitis-
[Through oral mucosal epithelium, virus penetrates a neural ending and travels to the
trigeminal ganglion.]
Primary herpetic gingivostomatitis-
Symptoms:
- painful severe gingivitis with redness
- ulcerations with serofibrinous exudate
- edema accompanied by stomatitis
Primary herpetic gingivostomatitis:
Characteristics:
- Incubation period is one week.
- Formation of vesicles, which rupture, coalesce
and leave fibrin-coated ulcers. - Healing within 10 to 14 days.
- Formation of vesicles, which rupture, coalesce
Primary herpetic gingivostomatitis may be
asymptomatic in childhood, but may also give rise severe gingivostomatitis (painful severe gingivitis with redness, ulcerations with serofibrinous exudate and edema.
Primary herpetic gingivostomatitis:
The incubation period is
1 week
Primary herpetic gingivostomatitis:
A characteristic feature is formation of
vesicles, which rupture, coalesce, and leave fibrin coated ulcers.
Fever and lymphadenopathy are other classic features.
Hereditary gingival fibromatosis- Possible mechanism(s):
TGF-1 favor the accumulation of ECM.
May be located on chromosome 2 in human.
- β-glucuronidase:
a lysosomal enzyme degrades proteoglycans and ground substance
- Elastase: a proteolytic enzyme found in lysosomal granules of
neutrophil
Near Infrared (NIR) Spectroscopy
Measure of oxygen saturation of the tissues
The wavelength region 500 to 600 nm is dominated by the absorption from oxygenated hemoglobin (HbO2) and deoxygenated hemoglobin (Hb)
Volpe-Manhold Index: Determines the
quantity of supragingival calculus
Volpe-Manhold Index measures
Lingual surfaces of lower anteriors (#22-27)
Volpe-Manhold Index: Quantity is determined in
mm of calculus along the 2 diagonal and the central lines drawn over the lingual surface of each tooth
Volpe-Manhold Index: Index, expressed in mm, is computed for tooth, subject, population
Most frequently used calculus index in
longitudinal studies
B-o-P is a valid indicator for periodontal ——–. However, it is a poor indicator of periodontal ———-.
stability
breakdown
The Extent and Severity Index (ESI):
Agreement
Disease is defined as attachment loss >1mm
The Extent and Severity Index (ESI):
Extent
Proportion of tooth sites in a patient showing signs of destructive periodontitis
The Extent and Severity Index (ESI):
Severity
Amount of attachment loss at the diseased sites, expressed as a mean value
Bacterial plaque induces gingivitis, but ——- determines if CP will develop
host response
Primary herpetic gingivostomatitis-
Symptoms:
- painful severe gingivitis with redness
- ulcerations with serofibrinous exudate
- edema accompanied by stomatitis
Primary herpetic gingivostomatitis-
Characteristics:
- Incubation period is one week.
- Formation of vesicles, which rupture, coalesce
and leave fibrin-coated ulcers. - Healing within 10 to 14 days.
- Formation of vesicles, which rupture, coalesce
Recurrent herpetic infections
herpes labialis
Vermilion border and/or the skin adjacent to it. 20-40% of individuals with primary infection.
Recurrent herpetic infections
Diagnosis:
- generally considered an ------------. - ulcers in ------------.
aphtous ulceration
attached gingiva and hard palate
Herpes zoster-
Clinical:
Small ulcers usually on the —————.
- Latent in the ------------. - ---------- lesions.
tongue, palatal and gingiva
dorsal root ganglion
Unilateral
Hereditary gingival fibromatosis possible mechs:
TGF-beta1 favor the accumulation of ECM.
May be located on chromosome 2 in human.
Pyogenic granuloma of pregnancy-
Commonly arises from the ———- and has a ————-.
proximal gingival tissues
pedunculated base
Nonperiodonittis related abscess:
Root morphology alterations
Iatrogenic (endodontic perforation)
External root resorption
Cemental tears
Lichen planus:
——— alone is common.
Oral involvement
Lichen planus:
> Characteristic skin lesions
(Wickham striae).
Lichen planus: Various clinical appearances.
[papular, reticular, plaque-like, atrophic, ulcerative, bullous]
:Oral Lichenoid Lesions: *
subepithelial,band-like accumulation of lymphocytes and macrophages characteristic of a type IV hypersensitivity reaction.
Oral Lichenoid Lesions: examples
Examples: lesions in contact with dental restorations
lesions associated with various types of medications (NSAIDs, diuretics, beta-blockers etc)
a group of systemic diseases (liver disease)
Oral Lichenoid Lesions: Treatment:
Take biopsy (handling is different than regular biopsy) Take sample for culture if questioning candida inf
(about 38% of OLP cases have secondary inf)
A traumatic dental plaque control
Topical corticosteroids to control pain, discomfort
Pemphigoid
A group of disorders in which
autoantibodies towards components of the basement membrane result in detachment of the epithelium from the connective tissue
Pemphigoid: Histology:
Autoantibody reactions against hemidesmosome and
lamina lucida components.
Pemphigoid: ————– may be involved in the pathogenesis.
Complement-mediated cell destructive processes
Pemphigoid: Three types:
-
Bullous
- Benign Mucous Membrane -
Cicatricial (Scar formation)
Pemphigoid: Nicholsky sign
[Rubbing of the gingiva creates bulla formation]