Surgery- Plastics Flashcards

1
Q

What type of cells are recruited during the inflammation-sterilization phase of wound healing?

A

PMNs, Macrophages, Lymphocytes, Fibroblasts

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2
Q

What is the main chemotactic factor for fibroblasts during the proliferation phase?

A

PDGF

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3
Q

What is the maximum wound strength that can be achieved by a healed wound?

A

70-80% of original tissue’s tensile strength

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4
Q

This refers to dense collagen matrixes that lack dermal appendages.

A

Scar

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5
Q

What cells are responsible for wound contracture that persists for 4-6 weeks?

A

Myofibroblasts

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6
Q
Cytokines: Triggers mitosis of fibroblasts and keratinocytes and induces collagen production.
A. IFN-y
B. IGF-1
C. PDGF
D. TNF-a
A

B. IGF-1

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7
Q
Cytokines: Also triggers mitosis of fibroblasts and keratinocytes in addition to matrix production.
A. IFN-y
B. IGF-1
C. TGF-b
D. VEGF
A

C. TGF-b

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8
Q

The minimum tissue oxygen tension requirement for oxygenases to function properly.

A

~20 mmHg

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9
Q

What is the minimum bacterial load per gram of tissue that prevents wound healing?

A

10 to the fifth power/g tissue

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10
Q

This chronic disease impairs wound healing due to hypoxia, neuropathy, glycosylated protein malfunction and impaired immune cell localization.

A

Diabetes mellitus

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11
Q

What systemic factor that inhibits wound healing is due to a relative upregulation of matrix metalloproteinase 2 and 9 thereby decreases collagen synthesis?

A

Aging

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12
Q

The type of collagen that is the primary form in early phases of wound healing and persists in children, making scars less obvious.

A

Type III collagen

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13
Q

The type of collagen found in the lens of the eye.

A

Type IV collagen

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14
Q

The type of collagen that is found in healed wounds.

A

Type I collagen

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15
Q

The type of wound closure that occurs when tissues are not initially closed or are too extensive to close and instead are closed via tissue proliferation at skin edges.

A

Secondary closure

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16
Q

The type of closure that occurs when a wound is purposely left open or has remained open for >6-8 hours and is reapproximated at a later time.

A

Tertiary closure

17
Q

What is the basic gold standard suturing technique?

A

Simple interrupted

18
Q

What type of suturing technique has improved tissue eversion and better hemostatic properties especially when used on thick skins?

A

Horizontal mattress

19
Q

What type of suturing technique involves the superficial closure of the dermo-epidermal junction thus, minimizing external scars?

A

Subcuticular running

20
Q
Suture removal times: How many days?
Face
Neck/scalp
Trunk
Extremities
A

Face: 3-5 days
Neck/scalp: 5-7 days
Trunk: 10-14 days
Extremities: 10-14 days

21
Q

Inflammation occurs from the time of tissue injury until how many days?

A

3-4 days

22
Q

What is the recurrence rate for keloids with surgical therapy alone?

A

45-100%

23
Q

What is the most frequent complication resulting in free flap failure?

A

Venous congestion leading to flap ischemia

24
Q

This type of pedicled flap is an alternative to TRAM reconstruction in patients who have anatomic contraindications.

A

Latissimus dorsi flap

25
Q

Reconstructive flaps: Cutaneous flap used in areas where wounds cannot be closed primarily or where a skin graft would fail. Its blood supply is derived from the dermal-subdermal plexus or direct cutaneous unnamed vessels.

A

Local flap

26
Q

Reconstructive flap: Fasciocutaneous or myocutaneous flap used in wounds in which the defect is too large for a local advancement or requires additional tissue bulk. Its blood supply is based on named vessels or known cutaneous angiosomes.

A

Pedicled flap

27
Q

Reconstructive flap: Refers to tissue transfer to a distant location. The tissue requires microvascular anastomoses or arterial and venous systems.

A

Free flap

28
Q

What is the relative contraindication for performing implant reconstruction in post-mastectomy patients?

A

Adjuvant radiation therapy

29
Q

This process allows the skin graft to align its vessels and anastomose with the recipient bed to provide a blood supply until angiogenesis begins.

A

Inosculation