Surface Infections Flashcards
What are the natural surfaces
Urinary tract infection
GI tract infection
Skin
What are the prosthetic surfaces
The valves
The heart wires
The hip implants
Breast implants
What do the adhesins do
They would help the bacteria to bind to the host cells surface
On the mucosal surfaces, the skin
What are polysaccharide adhesins
Components of the bacteria cell membrane, cell wall or capsule
What organisms would be present in early post op infections.
Staph aureus
Enteriobacteriaceae
E.coli, proteus (gram negative bacteria)
What bacteria would be present in the long term post op infections
The staph aureus
The coagulase negative staphylococci (mainly the staph epidermis)
What organisms effect the cardiac pacing wire
Coagulase negative staphylococcus
Staph aureus
What are the stages of biofilm development
Attachement
Maturation
Dispersal
What is quorum sensing
The communication between the bacteria via the chemical s
What are the 3 principles of quorum sensing
Depends on:
Gene expression
The signalling molecules (this cell signalling by Autoinducers)
The cell receptors
What are the processes the pathogens infections on the surfaces
Attachment
The biofilm formation
The multiplication and invasion
Host reponse
What does quorum sensing control
The virulence factors
The biofilm formation
Spornation