Surface Epithelial Flashcards
what type of cells are epithelial cells
Aggregated polyhedral
How much extracellular matrix does epithelial have
small amount
what are the two types of epithelial
surface and glandular
what are some basic characteristics of epithelia PAT
Polarity , tightly adherent and avascular
what is the lamina propria
a layer of connective tissue that epithelial rest on
what is the basal pole
the region of the cell that faces the connective tissue
Apical pole
opposite facing the lumen
what is the basement membrane composed of
laminin type 4 collagen
how does the cell junction form
adhesion molecules
what is non celluar polylaccaride rich layer
the basement layer
what are cell junction maintained by
cytoskeleton elements
what is the funtion of occulding junction
form diffusion barrier
how are cytoskeleton classified
Microfilament - 5nm
Intermediate filament 10nm
microtubule 25 nm
how do microfilaments form a scaffolding
attach to each other to form a 3d intenral scaffolding
what do communicating junctions do
allow movement of molecules between cells
What is the Functions of epithelial
barrier, absorption, secretion, containment, locomotion
what is the function of anchoring and adherent junction
mechanical strength
what is adherence mediated by
presence of intracellular junction
what kind of cells have kerainsied
straified squamous
what is zonular occludes
band like
what kind of cells have ciliated or non cilated
simple columnar
what does the intrcellular junction form
cytoskeleton elements
What is the major link protiens of zonular occuldens
occuldins and claudins
what is the extracellular ligand of zonular occuldes
occuldins and claduins
Cytoskeleton compoents zonula occudens
actin filament
Intracellular attachment protien zonular occludens
ZOI 2 + 3
Zonula ahderenes major link
E cadherin catein complex
Extracellular ligand of zonula adherens
E cadherin catein complex
cytoskeleton components zonula adherens
Actin filament
Intracellular components for zonula adherens
a- actin vinculin
Major link protiens of macula adherens
cadherins (desmogelins desmocolins)
Macula adherens extracellular ligands
desmogelins + desmocolins
cytoskeleton compoentents macula adherens
intermediate filament , keratine and desmin
intracellular attachment protiens macula adherens
desmoplakin + plakoglobins
Gap Junction major link
connexin
extracellular ligands cap junction
connexin
cytoskeleton components gap junction
none
what is the junction complex
close association of serveal types of junction found in certain epithelial and other tissues
what is a desosome
macula adherence are also called desmosome
what is hemi desmosomes
another type of junction which is formed by half structures of desmosomes
