Surface Epithelial Flashcards

1
Q

what type of cells are epithelial cells

A

Aggregated polyhedral

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2
Q

How much extracellular matrix does epithelial have

A

small amount

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3
Q

what are the two types of epithelial

A

surface and glandular

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4
Q

what are some basic characteristics of epithelia PAT

A

Polarity , tightly adherent and avascular

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5
Q

what is the lamina propria

A

a layer of connective tissue that epithelial rest on

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6
Q

what is the basal pole

A

the region of the cell that faces the connective tissue

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7
Q

Apical pole

A

opposite facing the lumen

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8
Q
A
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9
Q

what is the basement membrane composed of

A

laminin type 4 collagen

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9
Q

how does the cell junction form

A

adhesion molecules

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9
Q

what is non celluar polylaccaride rich layer

A

the basement layer

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9
Q

what are cell junction maintained by

A

cytoskeleton elements

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9
Q

what is the funtion of occulding junction

A

form diffusion barrier

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9
Q

how are cytoskeleton classified

A

Microfilament - 5nm
Intermediate filament 10nm
microtubule 25 nm

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9
Q

how do microfilaments form a scaffolding

A

attach to each other to form a 3d intenral scaffolding

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9
Q

what do communicating junctions do

A

allow movement of molecules between cells

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10
Q

What is the Functions of epithelial

A

barrier, absorption, secretion, containment, locomotion

10
Q

what is the function of anchoring and adherent junction

A

mechanical strength

10
Q

what is adherence mediated by

A

presence of intracellular junction

10
Q

what kind of cells have kerainsied

A

straified squamous

10
Q

what is zonular occludes

A

band like

11
Q

what kind of cells have ciliated or non cilated

A

simple columnar

11
Q

what does the intrcellular junction form

A

cytoskeleton elements

12
Q

What is the major link protiens of zonular occuldens

A

occuldins and claudins

13
Q

what is the extracellular ligand of zonular occuldes

A

occuldins and claduins

14
Q

Cytoskeleton compoents zonula occudens

A

actin filament

15
Q

Intracellular attachment protien zonular occludens

A

ZOI 2 + 3

16
Q

Zonula ahderenes major link

A

E cadherin catein complex

17
Q

Extracellular ligand of zonula adherens

A

E cadherin catein complex

18
Q

cytoskeleton components zonula adherens

A

Actin filament

19
Q

Intracellular components for zonula adherens

A

a- actin vinculin

20
Q

Major link protiens of macula adherens

A

cadherins (desmogelins desmocolins)

21
Q

Macula adherens extracellular ligands

A

desmogelins + desmocolins

22
Q

cytoskeleton compoentents macula adherens

A

intermediate filament , keratine and desmin

23
Q

intracellular attachment protiens macula adherens

A

desmoplakin + plakoglobins

24
Q

Gap Junction major link

A

connexin

25
Q

extracellular ligands cap junction

A

connexin

26
Q

cytoskeleton components gap junction

A

none

27
Q

what is the junction complex

A

close association of serveal types of junction found in certain epithelial and other tissues

28
Q

what is a desosome

A

macula adherence are also called desmosome

29
Q

what is hemi desmosomes

A

another type of junction which is formed by half structures of desmosomes