Cartilage Flashcards
what are the connective tissues divided into
embryonic, soft, hard, and special connective tissue
what is type I
most abundant widely distributed
what is type II
hyaline and elastic cartilage
what is type III
recticual fibres
what is type IV
found in the basal lamina (does not form fibrils)
what is the composition connective tissue
semi rigid connective tissue
cartilage is avascular
how does cartilage get its nutrients
blood vessels surrounding connective tissue by diffusion through ECM
what does the cartilage lack
lacks lymphatic vessels and nerves
what are chondrocytes apart of
cells of cartilage
how is the extracellular cartilage shaped
amorphous (defined shapes)
what is type II fibres responsible for
provide mechanical stabillity
what allows deformation by compressive pressures
GAG’s and proteoglycans which attract water
what does chondroblats synthesize
ground substance and fibrous extracellular material
what does cartilage formation start with what
embryonic staellate mesenchymal cells
what does mesenchymal dfferentatie into
chondroblasts
what does multiplcation of chondroblasts forms
clusters 4 to 6 cells
what condroblasts mature into what
chondrocytes
what does chondrocytes maintian what
cartilage matrix
what are the stages of cartilage growth and where does it happen
appositional growth - at the edge
intersitial growth - within the matric
what does the perichondrium form
chondrogenic cells
what does chondorgenic cells differeinate into
chondroblasts
what do chondroblasts deposit
layers of the matrix at the periphery of the cartilage
what does the later stages of cartilage development
increases the thickness by appoisitonal growht
what does the intersitial growth
by the mitosis of chondrcytes
what does chondrotes divide and secrete in intersitial growth
matrix components and then move apart and become isolated in their individual lacunae
what time does intersitial growth ocucr
ealry phases of cartialg formation
how does cartilage repair if small injury
be repaired by activity of chondrogenic cells of perichondrium
these cells differentiate into chondroblasts migrate to the injured area and repair the defect by producing new cartilage matrix
how does cartilage repair if large
perichondrial cells cannot repair
instead perichondrial fibroblasts produce a scar of dense connective tissue that fills the defect in the cartilage
type of collagen fibres for hyaline
type II fibres
type of collagen fibres for fibrocartialge
type I + II Fibres
type of collagen fibres for elastic cartialge
type II fibres and elastic fibres
which type of cells have a perichondrium
Hyaline - expect articualr cartilage and epiphyseal plates
Elastic - Does
What are the main cells of hyaline cartilage
chondroblasts and chondrocytes
what is the main cells for elastic
chondroblasts and chondrocytes
what is the main cells for fibrocartialge
chondrocytes and fibroblasts
type of fibres in ECM for hyaline
Type II collagen
type of fibres in ECM for elastic
Type II collagen and Elastic fibres
type of fibres in ECM for firbocartialge
Type I and Type II collagen
What cartilages undergoes calcification
Hyaline - during endochronral bone formation (old age)
Fibrocartilage - during bone repair
Function of hyaline cartilage
resists compression
provides low friction surface for joints
strutucal support in respiratory
foundation for development of foetal skeleton
functions for elastic cartilage
provides flexible support for soft tissue
function fibrocartialge
resists deformation under stress
where is hyaline found
trachea and bonrchi
articulating , coastal and nasal cartilage
circoid thyroid and arytenoid cartilages of larynx
where is elastic found
pinna of the ear, epiglottis and autiodry tube
where is fibrocartilage found
intervertebral disc , pubic symphysis, intra articular disc of the sternoclvaicular joint and intra particular disc of the tmd joint
