Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Histology One > Ossification and Repair > Flashcards

Ossification and Repair Flashcards

1
Q

What is Endochondral Ossification

A

ttransformation of mesenchyme into carilaginous model which is later replaced by bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what is intramembranous

A

transformation of mesenchyme into cartilaginous model which is later replaced by bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are examples of intramembranous ossification?

A

bones of vault of the skull ~ frontal and parietal
also the manible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what does mesenchymal cells differentiate into

A

osteoblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what do the obsteblasts from mesenchymal cells do

A

begin synthesize and secrete osteoid at multi sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what do these entrapped cells become

A

osteocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what do the mesenchymal cells go in intramembraneous ossification

A

spindle shaped mesenchymal cells migrate and aggreagte into specific areas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what forms in the first stage of intramembraneous ossification

A

ossification centres form within thickened regions of mesenchyme

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

what is the second stage of intramembraneous ossification

A

osteoid undergoes calcification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is the third stage of intramembraneous ossification

A

woven bone and surrounding periosteum form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the fourth stage of intramembraenous ossification

A

lamellar bone replaces woven bone as compact and spongy bone forms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what does the mesenchymal cells differetiate into what

A

chondroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what does the chondroblasts form

A

cartilage model

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is the cartage model replced by

A

bony tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is endonchroal ossification in a nutshell

A

hyaline cartilage model of the bone to be formed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what is enchondral ossification responsible for forming

A

short and long bones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what does the bone collar do

A

impeds diffusion of oxygen and nutrients into underlying cartilage and promotes degenerative changes

18
Q

what does diffusion of nutrients allow

A

calification matrix

19
Q

what trimester does bony collar formation start

A

second

20
Q

what is the composition of bone at the time of birth

A

half cartilage half bone

21
Q

what is the epiphyseal plate responsible for

A

growth in length of bone and it disappears in mature adults

22
Q

what is the resting zone

A

hyaline cartilage with typical chondrocytes

23
Q

what is proliferative zone

A

rapidly dividing chondrocytes

24
Q

what is the hypertrophic cartilage zone

A

swollen chondrocytes whose cytoplasm has accumulated glycogen

25
Q

what is the calfified cartilage zone

A

loss of the chondroytes by apotosis and calfication

26
Q

what is the ossification zone

A

appearance of first bone tissue

27
Q

what are bony spicules have in endochondral ossification

A

calcified cartilage scaffold from the eipihyseal growth p,ate

28
Q

what are the four stages of bone repair

A

hematoma formation
fibrocartilginous callus formation
bont callus formation
bone remodelling

29
Q

what happens to the blood vessels when bone fractured

A

blood vessels are disrupted and the bone cells die

30
Q

what do damaged blood vessels form

A

reduce localised hemorahe and form blood clots

31
Q

what happens to blood in the second stage of bone growth

A

are removed by marophages

32
Q

in the second stage of bone growth how is adjacent bone matrix resolved by

A

osteoplast

33
Q

what do the periosteum and enosteum do during bone growth

A

intense proliferation by producing soft callus and fibrocartilage like tissue

34
Q

what is formed in the third stage of bone growth

A

primary bone is formed by combination of endochondral and intermembraous ossification

35
Q

what does primary bone do

A

unite the extrememtied of the fractured bone

36
Q

what does primary bone look like

A

irregulary formed traceulae

37
Q

what will happen to the primary bone

A

gradually resolved and replaced by secondary bone

38
Q

what is osteoporosis

A

bone fracture easy

39
Q

what can be used to help osteoporosis

A

hormones such as calcitonin inhibits bone destruction and parathyroid hormone promotes the bone destruction.

40
Q

what is paget’s disease

A

causes erosion of bone because of uncontrolled osteoclast activity

41
Q

what is osteomalacia

A

failure of osteoid to properly mineralise
insufficient diet of calcium or renal dysfunction leading to excessive phosphate loss in urine

Histology One (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions