SUD Lecture Flashcards
All addicting substances and behaviors
directly or indirectly affect the ? pathways,
dopamine
As ? is the
primary neurotransmitter associated with the reinforcing effect of the substance.
dopamine
DSM criteria for alcohol use disorder (at least ? of the following occurring in a ?-month
period)
2
12
Screening of substance use disorders
Diagnostic Tools - ?
None
Screening of substance use disorders
3 Screening Tools
CAGE
AUDIT – C
AUDIT
CAGE: ? question screening
4
AUDIT – C: ? question screening
3
AUDIT: ? question screening
10
Have you ever felt the
need to cut down on
your drinking?
CAGE
C
Have people annoyed you by
criticizing your drinking?
CAGE
A
Have you ever
felt guilty about drinking?
CAGE
G
Have you ever felt you
needed a drink first thing
in the morning to steady
your nerves or to get rid
of a hangover (eye-
opener
CAGE
E
What do each C mean
CAGE
Cut
What do A mean
CAKE
Annoyed
What does G mean
CAGE
Guilt
What does E mean
CAGE
Eye opener
AUDIT-C
A score greater than ? for men is at risk
4
AUDIT-C
A score greater than ? for women is at risk
2
Pharmacokinetics of Alcohol
Primarily metabolized in the ?
leading to ?
Liver
Cirrhosis
Pharmacokinetics of Alcohol
?% is excreted in sweat, breath and urine
10
Pharmacokinetics of Alcohol
? is the chemical name for alcohol
Ethanol
10% is excreted in 3?
sweat, breath and urine
Responsible for “rewarding” effect
Dopamine
The inability to withhold a prepotent response or suppress an inappropriate or unwanted behavior which is casue d by alcohol ingestion
Disinhibition
Alcohol effects
S
D
R
D
S
N
Sedation,
Disinhibition,
Relaxation,
Decrease coordination
Slurred speech
Nausea
Alcohol Overdose
R
C
Respiratory depression
Cardiac arrest
Alcohol Withdrawal
T
S
E
D
Tremors,
seizures,
elevated temperature pulse blood pressure
Delirium tremens
Alcohol
Prolonged use : Effects or systems of the body. Can lead to other ? 2
dependencies, and malnutrition
Causes agitation, restlessness, anxiety, and sweating.
Alcohol Withdrawal vs. Alcohol Effects/overdose
Alcohol Withdrawal
Can lead to slowed brain function, cognitive impairment, coma.
Alcohol Withdrawal vs. Alcohol Effects/overdose
Alcohol Effects/overdose
VS:
elevated HR,
elevated temp,
normal or slightly elevated systolic BP
Mild, Moderate, Severe AWS
Mild
Ranges for normal temp in F
97 to 99
Ranges for normal temp in C
36.1 to 37.2
With alcohol withdrawal syndrome is ? of BP is priorty
Systolic
VS:
Heart rate 100-120 BPM elevated systolic BP
Elevated temperature
Mild, Moderate, Severe AWS
Moderate
VS
Heart rate 120 - 140 BPM; Elevated Systolic and Diastolic BP
Elevated temperature
Mild, Moderate, Severe AWS
Severe