BIPOLAR DISORDERS AND ANTIMANIC AGENTS Flashcards

1
Q

Bipolar I
Bipolar II
Cyclothymic Disorder

A
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2
Q

Bipolar I Diagnostic Criteria

At least ? Manic Episode

A

1

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3
Q

Major depressive episodes are common in
bipolar I disorder but are ? for the diagnosis of bipolar I disorder.

A

not required

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4
Q

Bipolar I Diagnostic Criteria

Elevated, expansive, or irritable mood and
increased activity/energy for at least ? week

A

1

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5
Q

Diagnostic Criteria for Mania
Marked ? in functioning

A

impairment

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6
Q

Marked impairment in functioning

A

Diagnostic Criteria for Mania

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7
Q

Mania Symptoms mnemonic

A

DIGFAST

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8
Q

DIGFAST

A

Mania Symptoms mnemonic

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9
Q

Mania Symptoms mnemonic
DIGFAST

D

A

Distractibility up

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10
Q

Mania Symptoms mnemonic
DIGFAST

I

A

Irresponsibility

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11
Q

Mania Symptoms mnemonic
DIGFAST

G

A

Grandiosity

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12
Q

an exaggerated sense of one’s importance, power, knowledge, or identity

I am going to be the next big thing to every exist.

A

Grandiosity

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13
Q

Mania Symptoms mnemonic
DIGFAST

F

A

Flight of Ideas

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14
Q

Mania Symptoms mnemonic
DIGFAST

A

A

Activity increases up

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15
Q

Mania Symptoms mnemonic
DIGFAST

S

A

Sleep decreases

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16
Q

Mania Symptoms mnemonic
DIGFAST

T

A

Talkativeness up

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17
Q

Which only requires only one mania eposide

Bipolar I
Bipolar II
Cyclothymic Disorder

A

Bipolar I

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18
Q

At least one hypomanic episode + a major depressive episode (required)

Bipolar I
Bipolar II
Cyclothymic Disorder

A

Bipolar II

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19
Q

Bipolar II
At least ? hypomanic episode +
a ? episode (required)

A

one

major depressive

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20
Q

Hypomania: Elevated, expansive,
or irritable mood and increased
activity/energy for at least 4 days

Bipolar I
Bipolar II
Cyclothymic Disorder

A

Bipolar II

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21
Q

Bipolar II

Hypomania: Elevated, expansive,
or irritable mood and increased
activity/energy for at least ? days

A

4

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22
Q

What is a lesser version of Mania

A

Hypomania

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23
Q

What a more heighted version of hypomania

A

Mania

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24
Q

Maniac for 7 days without major depression

Bipolar I
Bipolar II
Cyclothymic Disorder

A

Bipolar I

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25
Hypomaia for 4 days with major depression Bipolar I Bipolar II Cyclothymic Disorder
Bipolar II
26
Diagnostic Criteria for Mania Is ? or more symptooms of mania
three
27
Chronic fluctuating mood * For at least 2 years, for at least 50% of the time, here have been multiple Bipolar I Bipolar II Cyclothymic Disorder
Cyclothymic Disorder
28
Hypomanic and Depressive episodes without meeting full criteria Bipolar I Bipolar II Cyclothymic Disorder
Cyclothymic Disorder
29
Cyclothymic Disorder Chronic fluctuating mood * For at least ? , for at least 50% of the time, there have been multiple:
2 years
30
What is the main(First) drug to treat Bipolar Disorders
Lithium
31
What Is Lithium
Mood Stablizer
32
First drug by the FDA to be used for Bipolar Disorder?
Lithium
33
Avoid alcohol and other CNS depressant drugs
Lithium
34
Lithium Drug interactions
ACE Inhibitors(pril) Diuretics(depltes water and sodium from body) TCA - antihistimine/anticholergic drugs Nsaids
35
Lithium ? [Na] --> ? [Li]
Decreased Increased
36
Lithium Dehydration can ? serum concentration
increase
37
Lithium serum level of ? to ? mEq/L
0.6 to 1.2 mEq/L
38
Lithium Monitor at least ? days after dose changes
5
39
Lithium Every ? months while in maintenance
1-3
40
Lithium What are the labs you check
Lithium Levels, BUN, Creatine (Kidneys)
41
Lithium Thyroid must be assessed ? !
annually
42
Goiter
Thyroid related-
43
Lithium Less than 1.5
Common Adverse Reactions
44
Lithium 1.5 to 2.0
Early Indication
45
Lithium 2.0 to 2.5
Advance Indication
46
Lithium >2.5
Severe Toxicity
47
Diarrhea, Nausea, Vomiting, Thirst, Polyuria, Muscle Weakness, Fine Hand Tremors, Slurred Speech and Lethargy
Lithium Common Adverse Effects
48
Fine hand Tremors
Lithium Common Adverse Effects
49
Confusion, Sedation, Poor Coordination, Coarse Tremors, Cont GI Distress N/V/D
Lithium Early Indications
50
Coarse Tremors
Lithium Early Indications
51
Extreme Polyuria, Tinnitus, Giddiness, Jerking Movement , Blurred Vision, Ataxia, Seizure, Sev Hypotension, Coma , Death from RR
Lithium Advanced Indications
52
Jerking Movement
Lithium Advanced Indications
53
Rapid condition to death or coma
Lithium Severe Toxicity
54
Hemodialysis
Lithium Severe Toxicity
55
Lithium Mnemonic
Lithium
56
Lithium Mnemonic L
Levels (0.6-1.2 mEq/L)
57
Lithium Mnemonic I
Increased urination (polyuria)/ Insipidus
58
a rare condition where you pee a lot and often feel thirsty
Insipidus
59
Lithium Mnemonic T
Tremors/Thirst
60
Lithium Mnemonic H
Hypothyroidism
61
Lithium Mnemonic I2
INTERACTIONS ACE Inhibitors(pril) Diuretics(depltes water and sodium from body) TCA - antihistimine/anticholergic drugs Nsaids
62
Lithium Mnemonic U
Upset stomach
63
Lithium Mnemonic M
Muscle weakness/ Miscellaneous- EKG changes)
64
What has Blurred vision, nystagmus and diplopia N/V Hedaches. as side effect
Valproic acid Lithium Carbamazepine LAMOTRIGINE
65
What does Valproic acid, Lithium, Carbamazepine, LAMOTRIGINE have in common
Vision Distrubance Burred vision, nystagmus and diplopia N/V Headaches
66
Black Box: Hepatotoxicty + Pancreatitis + Teratogenic
Valproic acid
67
Valproic acid Monitor ? + ? periodically
Monitor LFTs + amylase periodically
68
Jaundice
Valproic acid
69
Rarely Thrombocytopenia
Valproic acid
70
Which put more at risk of bruising
Valproic acid
71
Used after Lithuim fails
CARBAMAZEPINe
72
? Stevens-Johnson syndrome, bone marrow suppression leading to anemia and agranulocytosis
CARBAMAZEPINe
73
Black box: Stevens-Johnson syndrome
LAMOTRIGINE Carbamazepine
74
Black box: Stevens-Johnson syndrome symptoms 3
Fever, Rash, Mouth sores
75
All The mediation on this test will have CNS isConcerns to avoud driving and Operating Heavy Machinery right
Yes
76
CNS Effects
Visual Distrubance, and Dizzieness, drowiness, Headaches, Catiuon while driving
77
Carbamazepine Check ?
BMP (Na, BUN)
78
Carbamazepine What disease state should we be cautious with? 3
Kidney, Heart Failure, autoimmune disease.
79
Carbamazepine Administration Give ? food (can cause GI symptoms) Can give at ?, if possible, to sleep through symptoms
With bedtime
80
Carbamazepine Due to ? * Periodic checks of ? * Report ?
bone marrow suppression CBC fever/sore throught
81
Due to bone marrow suppression
Carbamazepine
82
When Stevens-Johnson Syndrome (SJS) Appears what should you do
Stop Medication.
83
Slow titration regimen
LAMOTRIGINE
84