SUD 2 Flashcards by Shaquan Moore

Increase GABA, depress CNS

Barbiturates
Opioids

Barbiturates

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Treats
seizures
sedatives
insomnia
pain management/headache

Barbiturates
Opioids

Barbiturates

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Medications

Phenobarbital (Solfoton)
Butalbital (Fioricet)
Amobarbital (Tuinal)

Barbiturates
Opioids

Barbiturates

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Barbiturates
Withdrawal symptoms ? hour after last dose

8-12

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Gradual reduction of medication

Barbiturates
Opioids

Barbiturates

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Minor – N/V, tremor, muscle twitching, anxiety, orthostatic hypotension, dizziness, progressive weakness, insomnia, visual perception
disturbances

Barbiturates
Opioids

Barbiturates

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Life threatening – delirium, convulsions

Barbiturates
Opioids

Barbiturates

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MOA
Mimic endogenous neurotransmitters by stimulating opioid receptors, increase release of dopamine

Barbiturates
Opioids

Opioids

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Used for
Pain management

Barbiturates
Opioids

Opioids

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Hydromorphone (Dilaudid)
Morphine

Barbiturates
Opioids

Opioids

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Codeine

Barbiturates
Opioids

Opioids

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Heroin

Barbiturates
Opioids

Opioids

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Methadone (Dolophine)

Barbiturates
Opioids

Opioids

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This drug group affect dopamine which means the pt will feel sedated

Barbiturates
Opioids

Opioids

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A feeling of great happiness or well-being

Euphoria

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reduced pupil size (constricted)

Barbiturates
Opioids

Opioids

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Affect mood, feelings of Euphoria or feeling normal, sedation, memory and concentration
difficulties,, reduced pupil size (constricted), constipation, urinary retention, decreased
libido

Barbiturates
Opioids

Opioids

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Overdose: Respiratory depression, stupor, coma

Barbiturates
Opioids

Opioids

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an excessively deep state of unresponsiveness

stupor

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stupor

Barbiturates
Opioids

Opioids

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Overdose: Respiratory depression, stupor, coma

Barbiturates
Opioids

Opioids

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This drug will only made someone more sedated leading to coma

Barbiturates
Opioids

Opioids

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For Opioids what drug is used to treat overdose

Naloxone (Narcan)

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Treatment for suspected opioid overdose – Naloxone (Narcan)

Barbiturates
Opioids

Opioids

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Opioids Withdrawal Syndrome: ? hours after last dose

36 -72

An excessive discharge of mucus from the nose

Rhinorrhea

withdrawal Syndrome yawning, rhinorrhea, diaphoresis, tremor, restlessness, irritability, bone pain, muscle spasms, chills, piloerection (goosebumps), N/V/D, watery eyes, anorexia Barbiturates Opioids

Opioids

Goosebumps

Piloerection

successful in withdrawal, doesn’t decrease cravings Clonidine Buprenorphine Naloxone Subutex

Clonidine

is a long-acting partial agonist that acts on the same receptors as heroin and morphine- relieves drug cravings and the patient doesn’t experience an elevated “high’ or the serious side effects Clonidine Buprenorphine Naloxone Subutex

Buprenorphine

Low dose ? produces enough agonist effect to enable opioid addicted patience to discontinue misuse of opioids without having withdrawal symptoms Clonidine Buprenorphine Naloxone Subutex

Buprenorphine

Are combined into one composition called Suboxone Clonidine Buprenorphine Naloxone Subutex

Buprenorphine Naloxone

Suboxone Clonidine Buprenorphine Naloxone Subutex

Buprenorphine Naloxone

Used for maintenance of opioid addiction; sublingually as one dose and can be repeated up 3X day Suboxone Subutex

Suboxone

Buprenorphine only medication, safe in pregnancy Suboxone Subutex

Subutex

Safe in pregnancy Clonidine Buprenorphine Naloxone Subutex

Subutex

Suboxone given ? as one dose and can be repeated up 3X day

sublingually

were combined to protect patient from overdose if misuse of opiates Clonidine Buprenorphine Naloxone Subutex

Buprenorphine Naloxone

Maintenance treatment for opioid addiction Methadone (Dolophine) Cocaine

Methadone (Dolophine)

Binds to opioid receptors in the CNS to produce analgesia, euphoria , sedation ; the same receptors that mediate the effects of endogenous opioids Methadone (Dolophine) Cocaine

Methadone (Dolophine)

Methadone – half-life ? hours

15-30

MOA Blocks norepinephrine and dopamine reuptake Methadone (Dolophine) Cocaine

Cocaine

Euphoria, alertness, anorexia, increased strength initial effects Methadone (Dolophine) Cocaine

Cocaine

Increased strength initial effects Methadone (Dolophine) Cocaine

Cocaine

Creates a feeling of a high Methadone (Dolophine) Cocaine

Cocaine

Effect Euphoria, dilated pupils, deep respirations, increased mental alertness, anorexia, increased strength, increased libido, intense paranoia Methadone (Dolophine) Cocaine

Cocaine

Feelings of bugs crawling under their skin (formication) Methadone (Dolophine) Cocaine

Cocaine

Feelings of bugs crawling under their skin

Formication

Sense foul smells, nasal septum perforation r/t snorting Methadone (Dolophine) Cocaine

Cocaine

respiratory and metabolic acidosis, arrythmias and coronary artery spasms Methadone (Dolophine) Cocaine

Cocaine

Young adults – heart failure, stroke Methadone (Dolophine) Cocaine

Cocaine

Methylphenidate (Ritalin), Methylenedioxymethamphetamine (MDMA or ecstasy)- high rate of trading or selling in high school or college to increase alertness when completing assignments and exam performance Amphetamines Cocaine

Amphetamines

Dilated pupils Methadone (Dolophine) Cocaine

Cocaine

PNS effects – elevated blood pressure, tachycardia, palpitations, increased respirations Amphetamines Cocaine

Both

Overdose: Cardiac arrhythmias or arrests Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Cycle motor retardation at first and then agitation Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Fatigue and then insomnia Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

vivid, unpleasant dreams Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Decreased appetite Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

a state of feeling unhappy, uneasy, or dissatisfied

dysphoria

Severe dysphoria and anxiety Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

? withdrawal is not as pronounced as ? withdrawal

Amphetamines Cocaine

Alternates with use of depressants Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Weight loss and resulting malnutrition and increased susceptibility to infectious diseases. Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

May produce schizophrenia like syndrome with paranoid ideation thought disturbance hallucinations and stereotype movement events Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

schizophrenia like syndrome Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Deviated nasal septum and irreversible nasal damage secondary to snorting Amphetamines Methadone (Dolophine) Cocaine

Amphetamines Cocaine

Stimulates the nervous system by binding to serotonin receptors Amphetamines Cocaine LSD

LSD

Synethesia - tasting a sound or smelling a color Amphetamines Cocaine LSD

all

Dilated pupils Amphetamines Cocaine LSD

all

Elevated blood pressure Amphetamines Cocaine LSD

all

Tachycardia Amphetamines Cocaine LSD

all

Shaking Amphetamines Cocaine LSD

all

CNS effects – impaired judgement, distortions, unreality and perceptual variations Amphetamines Cocaine LSD

all

Which of the following has caffine Coffee Tea Cocoa Soft drinks Chocolate OTC medications (cold medications, analgesics) Appetite suppressants Energy drinks

All

Effects: Stimulation, inexhaustibility, increased mental acuity Caffeine Nicotine

Caffeine

Overdose: insomnia, excitement, nervousness, restlessness, flushing, diuresis, muscle twitching, gastrointestinal disturbance, tachycardia or cardiac arrhythmia, agitation, rambling thought process and speech Caffeine Nicotine

Caffeine

Withdrawal syndrome: headache, decreased psychomotor performance, difficulty concentrating, yawning, nausea, fatigue, drowsiness Caffeine Nicotine

Caffeine

Most prevalent in –(Menatal Health d/o) schizophrenia bipolar disorder post traumatic stress disorder alcohol and illicit drug use Caffeine Nicotine

Nicotine

Acts as an agonist of the nicotine cholinergic receptor sites stimulating the automatic ganglia in the parasympathetic and sympathetic nervous system Caffeine Nicotine

Nicotine

The release of ? by nicotine increased the risk for atherosclerosis and heart disease

epinephrine

Effects: stimulation, appetite suppression, enhance performance, increased alertness Caffeine Nicotine

Nicotine

Overdose: anxiety Caffeine Nicotine

Nicotine

Withdrawal syndrome: mood changes; anxiety, cravings and physiological changes; sleep disturbances, headaches, poor concentration, increased appetite, gastric disturbance Caffeine Nicotine

Nicotine

Prolong use: increase risk for developing cardiac disease lung cancer , or COPD Caffeine Nicotine

Nicotine

Which suppressing appetite and causes weight loss as an effect Caffeine Nicotine

Nicotine

Which can cause weight gain and increased appetite with withdrawal Caffeine Nicotine

Nicotine

Transdermal Patches (rotate skin sites) Nicotine Gum

Nicotine Cessation

Nasal Spray Nasal Inhaler

Nicotine Cessation

Medications – Antidepressant Bupropion- Zyban

Nicotine Cessation

Varenicline tartrate (Chantix) – reduces cravings

Nicotine Cessation

Auricular therapy – ear acupressure

Nicotine Cessation

Electronic cigarettes

Nicotine Cessation