SUD 2 Flashcards
Increase GABA, depress CNS
Barbiturates
Opioids
Barbiturates
Treats
seizures
sedatives
insomnia
pain management/headache
Barbiturates
Opioids
Barbiturates
Medications
Phenobarbital (Solfoton)
Butalbital (Fioricet)
Amobarbital (Tuinal)
Barbiturates
Opioids
Barbiturates
Barbiturates
Withdrawal symptoms ? hour after last dose
8-12
Gradual reduction of medication
Barbiturates
Opioids
Barbiturates
Minor – N/V, tremor, muscle twitching, anxiety, orthostatic hypotension, dizziness, progressive weakness, insomnia, visual perception
disturbances
Barbiturates
Opioids
Barbiturates
Life threatening – delirium, convulsions
Barbiturates
Opioids
Barbiturates
MOA
Mimic endogenous neurotransmitters by stimulating opioid receptors, increase release of dopamine
Barbiturates
Opioids
Opioids
Used for
Pain management
Barbiturates
Opioids
Opioids
Hydromorphone (Dilaudid)
Morphine
Barbiturates
Opioids
Opioids
Codeine
Barbiturates
Opioids
Opioids
Heroin
Barbiturates
Opioids
Opioids
Methadone (Dolophine)
Barbiturates
Opioids
Opioids
This drug group affect dopamine which means the pt will feel sedated
Barbiturates
Opioids
Opioids
A feeling of great happiness or well-being
Euphoria
reduced pupil size (constricted)
Barbiturates
Opioids
Opioids
Affect mood, feelings of Euphoria or feeling normal, sedation, memory and concentration
difficulties,, reduced pupil size (constricted), constipation, urinary retention, decreased
libido
Barbiturates
Opioids
Opioids
Overdose: Respiratory depression, stupor, coma
Barbiturates
Opioids
Opioids
an excessively deep state of unresponsiveness
stupor
stupor
Barbiturates
Opioids
Opioids
Overdose: Respiratory depression, stupor, coma
Barbiturates
Opioids
Opioids
This drug will only made someone more sedated leading to coma
Barbiturates
Opioids
Opioids
For Opioids what drug is used to treat overdose
Naloxone (Narcan)
Treatment for suspected opioid overdose – Naloxone (Narcan)
Barbiturates
Opioids
Opioids
Opioids
Withdrawal Syndrome: ? hours after last dose
36 -72
An excessive discharge of mucus from the nose
Rhinorrhea
withdrawal Syndrome
yawning, rhinorrhea, diaphoresis, tremor, restlessness, irritability,
bone pain, muscle spasms, chills, piloerection (goosebumps), N/V/D, watery eyes, anorexia
Barbiturates
Opioids
Opioids
Goosebumps
Piloerection
successful in withdrawal, doesn’t decrease cravings
Clonidine
Buprenorphine
Naloxone
Subutex
Clonidine
is a long-acting partial agonist that acts on the same receptors as heroin and morphine- relieves drug cravings and the patient doesn’t experience an elevated “high’ or the serious side effects
Clonidine
Buprenorphine
Naloxone
Subutex
Buprenorphine
Low dose ? produces enough agonist effect to enable opioid addicted patience to
discontinue misuse of opioids without having withdrawal symptoms
Clonidine
Buprenorphine
Naloxone
Subutex
Buprenorphine
Are combined into one composition called Suboxone
Clonidine
Buprenorphine
Naloxone
Subutex
Buprenorphine
Naloxone
Suboxone
Clonidine
Buprenorphine
Naloxone
Subutex
Buprenorphine
Naloxone
Used for maintenance of opioid addiction; sublingually as one dose and can be repeated up 3X day
Suboxone
Subutex
Suboxone
Buprenorphine only medication, safe in pregnancy
Suboxone
Subutex
Subutex
Safe in pregnancy
Clonidine
Buprenorphine
Naloxone
Subutex
Subutex
Suboxone given ? as one dose and can be repeated up 3X day
sublingually
were combined to protect patient from overdose if misuse of opiates
Clonidine
Buprenorphine
Naloxone
Subutex
Buprenorphine
Naloxone
Maintenance treatment for opioid addiction
Methadone (Dolophine)
Cocaine
Methadone (Dolophine)
Binds to opioid receptors in the CNS to produce analgesia, euphoria , sedation ; the same receptors that mediate the effects of endogenous opioids
Methadone (Dolophine)
Cocaine
Methadone (Dolophine)
Methadone – half-life ? hours
15-30
MOA Blocks norepinephrine and dopamine reuptake
Methadone (Dolophine)
Cocaine
Cocaine
Euphoria, alertness, anorexia, increased strength initial effects
Methadone (Dolophine)
Cocaine
Cocaine
Increased strength initial effects
Methadone (Dolophine)
Cocaine
Cocaine
Creates a feeling of a high
Methadone (Dolophine)
Cocaine
Cocaine
Effect
Euphoria, dilated pupils, deep respirations, increased mental alertness, anorexia, increased strength, increased libido, intense paranoia
Methadone (Dolophine)
Cocaine
Cocaine
Feelings of bugs crawling under their skin (formication)
Methadone (Dolophine)
Cocaine
Cocaine
Feelings of bugs crawling under their skin
Formication
Sense foul smells, nasal septum perforation r/t snorting
Methadone (Dolophine)
Cocaine
Cocaine
respiratory and metabolic
acidosis, arrythmias and coronary artery spasms
Methadone (Dolophine)
Cocaine
Cocaine
Young adults – heart failure, stroke
Methadone (Dolophine)
Cocaine
Cocaine
Methylphenidate (Ritalin), Methylenedioxymethamphetamine (MDMA or ecstasy)- high rate of trading
or selling in high school or college to increase alertness when completing assignments and exam
performance
Amphetamines
Cocaine
Amphetamines
Dilated pupils
Methadone (Dolophine)
Cocaine
Cocaine
PNS effects – elevated blood pressure, tachycardia, palpitations, increased respirations
Amphetamines
Cocaine
Both
Overdose: Cardiac arrhythmias or arrests
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Cycle motor retardation at first and then agitation
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Fatigue and then insomnia
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
vivid, unpleasant dreams
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Decreased appetite
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
a state of feeling unhappy, uneasy, or dissatisfied
dysphoria
Severe dysphoria and anxiety
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
? withdrawal is not as
pronounced as ? withdrawal
Amphetamines
Cocaine
Alternates with use of depressants
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Weight loss and resulting malnutrition and increased
susceptibility to infectious diseases.
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
May produce schizophrenia like syndrome with
paranoid ideation thought disturbance hallucinations and stereotype movement events
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
schizophrenia like syndrome
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Deviated nasal septum and irreversible nasal damage secondary to snorting
Amphetamines
Methadone (Dolophine)
Cocaine
Amphetamines
Cocaine
Stimulates the nervous system by binding to serotonin receptors
Amphetamines
Cocaine
LSD
LSD
Synethesia - tasting a sound or smelling a color
Amphetamines
Cocaine
LSD
all
Dilated pupils
Amphetamines
Cocaine
LSD
all
Elevated blood pressure
Amphetamines
Cocaine
LSD
all
Tachycardia
Amphetamines
Cocaine
LSD
all
Shaking
Amphetamines
Cocaine
LSD
all
CNS effects – impaired judgement, distortions, unreality and perceptual variations
Amphetamines
Cocaine
LSD
all
Which of the following has caffine
Coffee
Tea
Cocoa
Soft drinks
Chocolate
OTC medications (cold medications, analgesics)
Appetite suppressants
Energy drinks
All
Effects: Stimulation, inexhaustibility, increased mental acuity
Caffeine
Nicotine
Caffeine
Overdose: insomnia, excitement, nervousness, restlessness, flushing, diuresis, muscle twitching,
gastrointestinal disturbance, tachycardia or cardiac arrhythmia, agitation, rambling thought process
and speech
Caffeine
Nicotine
Caffeine
Withdrawal syndrome: headache, decreased psychomotor performance, difficulty concentrating,
yawning, nausea, fatigue, drowsiness
Caffeine
Nicotine
Caffeine
Most prevalent in –(Menatal Health d/o) schizophrenia
bipolar disorder
post traumatic stress disorder
alcohol and illicit drug use
Caffeine
Nicotine
Nicotine
Acts as an agonist of the nicotine cholinergic receptor sites stimulating the automatic
ganglia in the parasympathetic and sympathetic nervous system
Caffeine
Nicotine
Nicotine
The release of ? by nicotine increased the risk for atherosclerosis and heart disease
epinephrine
Effects: stimulation, appetite suppression, enhance performance, increased alertness
Caffeine
Nicotine
Nicotine
Overdose: anxiety
Caffeine
Nicotine
Nicotine
Withdrawal syndrome: mood changes; anxiety, cravings and physiological changes; sleep disturbances,
headaches, poor concentration, increased appetite, gastric disturbance
Caffeine
Nicotine
Nicotine
Prolong use: increase risk for developing cardiac disease lung cancer , or COPD
Caffeine
Nicotine
Nicotine
Which suppressing appetite and causes weight loss as an effect
Caffeine
Nicotine
Nicotine
Which can cause weight gain and increased appetite with withdrawal
Caffeine
Nicotine
Nicotine
Transdermal Patches (rotate skin sites)
Nicotine Gum
Nicotine Cessation
Nasal Spray
Nasal Inhaler
Nicotine Cessation
Medications – Antidepressant Bupropion- Zyban
Nicotine Cessation
Varenicline tartrate (Chantix) – reduces cravings
Nicotine Cessation
Auricular therapy – ear acupressure
Nicotine Cessation
Electronic cigarettes
Nicotine Cessation