Psychosis Flashcards
A collection of symptoms affecting the mind and impairing one’s ability to determine what is real. Common symptoms include hallucinations, delusions, disorganized thought and/or behavior.
Psychosis
Type of Hallucinations
Auditory
Visual
Tactile
Olfactory
Gustatory
sensations of touch without any physical stimulus.
Auditory
Visual
Tactile
Olfactory
Gustatory
Tactile
Which is common
Auditory
Visual
Tactile
Olfactory
Gustatory
Auditory
Which is Rare
Auditory
Visual
Tactile
Olfactory
Gustatory
Olfactory
Gustatory
Fixed false belief
Fixed = does not change if presented with evidence to the contrary
Delusions
Type of Delusions
P
R
S
R
G
N
E
B
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
A false belief that someone is being mistreated or harmed, or that someone close to them is being mistreated or harmed.
The police are following me because they want to torture me
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Persecutory
A false belief that is implausible, not based on normal life experiences, and not part of cultural practices.
Believing that aliens have removed your internal organs and replaced them with someone else’s
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Bizarre
A common psychotic symptom that involves believing that neutral events have special significance and refer to the individual personally.
That a song is about them
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Referential
a person believes that someone else is in love with them, even if that person is a stranger or celebrity
Billie Jean is not my lover, but she says I am the one
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Erotomanic
False beliefs about the body that are a type of delusional disorder
The person believes they are infested with parasites or insects
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Somatic
A type of psychopathological belief that one or more aspects of reality do not exist or have been destroyed
Believing that one’s face and body are non-existent
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Nihilistic
Any delusion associated with religious content
Believing that you are being punished for a sin
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Religious
A false belief that someone has special powers, wealth, or identity
Believing you have extraordinary talents or superpowers
Persecutory
Referential
Somatic
Religious
Grandiose
Nihilistic
Erotomanic
Bizarre
Grandiose
The repetition of words or phrases spoken by someone else
Echolalia
Echopraxia
Echolalia
The copying someone else’s physical movements or facial expressions
Echolalia
Echopraxia
Echopraxia
To be diagnosed with Schizophrenia you most have ? symptoms with last ? months
2 or more
Greater than 6 months
A disorder that disrupts a person’s awareness of the world around them
Catatonia
An effect that is being added to the patient
Positive symptoms vs Negative Symptoms
Positive symptoms
An effect that is being taken away or diminished from the patient
Positive symptoms vs Negative Symptoms
Negative Symptoms
Delusions
Positive symptoms vs Negative Symptoms
Positive symptoms
Avolition (lack of motivation)
Positive symptoms vs Negative Symptoms
Negative Symptoms
Hallucinations
Positive symptoms vs Negative Symptoms
Positive symptoms
Anhedonia (inability to experience joy or pleasure)
Positive symptoms vs Negative Symptoms
Negative Symptoms
Bizarre Behavior
Positive symptoms vs Negative Symptoms
Positive symptoms
Alogia (poverty of speech)
Positive symptoms vs Negative Symptoms
Negative Symptoms
Disorganization
Positive symptoms vs Negative Symptoms
Positive symptoms
Blunted/flat affect( reduction in the outward expression of emotion)
Positive symptoms vs Negative Symptoms
Negative Symptoms
Social Withdrawal
Positive symptoms vs Negative Symptoms
Negative Symptoms
Attention & *cognitive deficits
Positive symptoms vs Negative Symptoms
Negative Symptoms
Schizophrenia Onset
2
Late in Adolescence
Earlier in Males
Schizophrenia is the ? leading cause of disability
9th
Schizophrenia Treatment
Primarily life-long pharmacologic treatment Often preference to utilize ? for improved adherence
Long Acting Injectables (LAI)
Schizophrenia Treatment
For uncontrolled symptoms
Electroconvulsive Therapy
Schizophrenia Treatment
The third one ?
Psychosocial
Schizophrenia
Treatment
Psychosocial
? – for psychosis
? training
Promote ?
Treat ??
? Support
CBT
Social skills
coping skills
comorbidities such as SUD, anxiety
Vocational
Indicated for acute and maintenance
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
MOA: Dopamine antagonism (postsynaptic blockade), Ach and NE activity as well
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
Antipsychotics 1st Gen
Antipsychotics 2st Gen
Antipsychotics 3nd Gen
Formulations: 3 ?
PO, IM, LAI
Antipsychotics 1st Gen
Side Effects/Adverse Effect
Neuroendocrine: g?, m?
S?
W?
E?
N?
Side Effects/Adverse Effect
Neuroendocrine: gynecomastia, menstrual irregularities
Sedation
Weight gain
Extrapyramidal Symptoms (EPS)
Neuroleptic Malignant Syndrome (NMS)
Neuroendocrine: gynecomastia, menstrual irregularities
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
Haldol/haloperidol
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
Thorazine/chlorpromazine
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
Antipsychotics 1st Gen
Antipsychotics 2nd Gen
Antipsychotics 3nd Gen
BLACK BOX: Not approved for ? related psychosis.? implications
dementia
Cardiac
Neuroleptic Malignant Syndrome mnemonic
Hot, stiff, out of it
Hot, stiff, out of it
Neuroleptic Malignant Syndrome mnemonic
Neuroleptic Malignant Syndrome
Etiology not totally clear but likely dopamine blockade in ?
hypothalamus
Neuroleptic Malignant Syndrome Risk Factors
D
? month of treatment
? Predisposition
? dose or ? antipsychotics
Risk Factors
Dehydration
First month of treatment
Genetic Predisposition
Increasing dose or multiple antipsychotics
Neuroleptic Malignant Syndrome Symptoms
S? “?”
? Temperature
? Status
Autonomic Instability
HTN, tachycardia, diaphoresis, tachypnea
Severe Muscle Rigidity “Lead Pipe”
Elevated Temperature
Altered Mental Status
Autonomic Instability
HTN, tachycardia, diaphoresis, tachypnea
Neuroleptic Malignant Syndrome
Nursing Interventions
S?
C?
Monitor ? & ?
Expect orders for ? agonists (?)
and/or
? relaxants (? or ?)
Nursing Interventions
Stop Medication
Cool off
Monitor I/O & Vital Signs
Expect orders for dopamine agonists (bromocriptine) and/or muscle relaxants (dantrolene or benzodiazepines)
dopamine agonists (bromocriptine)
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Neuroleptic Malignant Syndrome
muscle relaxants (dantrolene or benzodiazepines)
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Neuroleptic Malignant Syndrome
Akathisia
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Dystonia
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Pseudoparkinsonism
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
inability to sit still
Akathisia
involuntary muscle spasms, stiffness
Dystonia
rigidity, tremor, slowed movement
Pseudoparkinsonism
? can occur due to medications that block dopamine receptors
pseudoparkinsonism
Treatment
Acute: Benztropine (Cogentin)
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Diphenhydramine (Benadryl) IM or IV
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Long term: daily oral anticholinergic therapy
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Uncontrollable facial movement such as lip smacking
Tardive Dyskinesia
pseudoparkinsonism
Tardive Dyskinesia
Tardive Dyskinesia: later onset, and harder/impossible to reverse
Uncontrollable facial movement such as lip smacking
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
Valbenazine (Ingrezza) Treats ?
Tardive Dyskinesia
pseudoparkinsonism
Tardive Dyskinesia
Deutetrabenazine (Austedo) Treats?
Tardive Dyskinesia
pseudoparkinsonism
Tardive Dyskinesia
Which is life-threatening
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Neuroleptic Malignant Syndrome
Not typically fatal but can significantly impact a person’s comfort and quality of life if not treated?
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
AIMS: Abnormal Involuntary movement scale is associated with?
Neuroleptic Malignant Syndrome
or
Extrapyramidal Symptoms
Extrapyramidal Symptoms
MOA: dopamine and serotonin antagonism
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
b. Antipsychotics 2nd Gen
Preferred due to side effects, not efficacy
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
Anticholinergic effects*
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
Hyperprolactinemia
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
Weight gain
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
All
metabolic syndrome
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
Agitation, insomnia
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
Weakness, fatigue, sedation
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c.Antipsychotics 3nd Gen
all
Cardiac Implications
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
All
Sexual dysfunction
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
EPS/NMS (but less likely)
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
EPS/NMS
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
a. Antipsychotics 1st Gen
Clozaril/clozapine
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
b. Antipsychotics 2nd Gen
High Risk, High Regulation Drug
Risk: Severe Neutropenia
Clozaril/clozapine
Invega/paliperidone
Clozaril/clozapine
Clozaril/clozapine
Monitoring:
? at initiation
Weekly absolute neutrophil count (ANC) for the first ? months
? for another 6 months
Then ? for duration of therapy
Monitoring:
CBC at initiation
Weekly absolute neutrophil count (ANC) for the first 6 months
Biweekly for another 6 months
Then monthly for duration of therapy
Which is not used first with b. Antipsychotics 2nd Gen
Clozaril/clozapine
Invega/paliperidone
Clozaril/clozapine
Often grouped with SGA/atypicals
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
c. Antipsychotics 3nd Gen
used as adjunctive or monotherapy in mood disorders
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
c. Antipsychotics 3nd Gen
MOA: partial dopamine agonist, serotonin-dopamine activity modulator
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
c. Antipsychotics 3nd Gen
Claims of being “weight neutral”
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
c. Antipsychotics 3nd Gen
Similar to 2nd Gen
a. Antipsychotics 1st Gen
b. Antipsychotics 2nd Gen
c. Antipsychotics 3nd Gen
c. Antipsychotics 3nd Gen
What I always have to remember about Anticholinergic Side Effects
Body stays in Sympathetic State
But Fluid production is bloked because the body cannot regulate it self in parasympathic is blocked.
Urine rentiontion
Sweat decreases
Dry Mouth
Schizophrenia Spectrum
Brief psychotic disorder
Less than ? month
1
Schizophrenia Spectrum
Schizophreniform
? months
1-6
Less than 1 month
Brief psychotic disorder
Schizophreniform
Brief psychotic disorder
1-6 months
Brief psychotic disorder
Schizophreniform
Schizophreniform
With Schizophrenia you checks signs of
3?
NMS
EPS
Anticholinergic Crisis
With Schizophrenia you have pt ? Balance
Promote Fluid
You will AIMS: Abnormal Involuntary movement scale to cheach for movent of al these disorders
Yes
what are used to diagnosis Schizophrenia
D
H
D
D or C Behavior
N
Delusions
Hallucinations
Disorganized speech
Disorganized or catatonic behavior
Negative symptoms
Schizoaffective Criteria
What 3 must pt have
Schizophrenia, Major depressive, Mania
Schizoaffective
Co-occurring ? and ? episode
psychosis ( Schizophrenia symptoms)
Mood d/o (Mania or MDD)
Schizoaffective
Delusions or hallucinations for ? weeks in the absence of a major mood episode
2 or more
Schizoaffective
Mood disorder symptoms must be present for >?% of total duration of illness
50
Schizoaffective is same treatment as Schizophreniia just atypical no 1st genration.
Delusional Disorder
Logical, stable, well-systematized delusions that occur in the absence of other psychiatric disorders for >?month
1
Delusional Disorder
All subtype of psychosis just two more ?
jellous
Mixed
Delusional Disorder
Goal: ?
reduce severity of delusion
Delusional Disorder
No ? only ? to treat it.
Meds
CBT