substance use disorder Flashcards

1
Q

criteria for substance use disorder

A
  • taking more of substance than intended
  • desire to cut down use but unable to
  • excessive time spent using/acquiring/recovering
  • craving
  • role disruption
  • interpersonal problems
  • reduction of important activities
  • use in physically hazardous situations
  • keep using depsite problems/consequences
  • tolerance
  • withdrawal
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2
Q

hwo many criteria does one need in timeframe to get diagnosis

A

2 or more in last year

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3
Q

what is withdrawal

A

negative psychological and physical symptoms when reducing/stopping use

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4
Q

what is tolerance

A

effects of drugs are less when usual amount is taken
larger doses needed to produce desired effect

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5
Q

examples of withdrawal symptoms

A

pain sensitivity
low mood
anxiety
vomiting
sweating
insomnia
flu like symptoms
lack of appetite

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6
Q

what do depressants do

A

sedate behaviour

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7
Q

examples of depressants

A

alcohol
sedatives
anxiolytic drugs

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8
Q

what do stimulants do

A

increase alertness and elevate mood

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9
Q

examples of stimulants

A

cocaine
nicotine
ecstasy
meth
coffee - not disorder

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10
Q

what do opiates do

A

produce analgesia and euphoria

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11
Q

examples of opiates

A

heroin
morphine
codeine

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12
Q

what do hallucinogens do

A

alter sensory perception

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13
Q

examples of hallucinogens

A

marijuana
lsd

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14
Q

drugs of abuse

A

inhalants
anabolic steroid
club/designer drugs

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15
Q

what does alcohol do to the brain

A

slows down CNS functioning
stimulates GABA receptors
increases levels of serotonin and dopamine
decrease glutamate

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16
Q

what happens when GABA receptors are stimulated

A

slows down neural firing
relaxation, reduced tensions
motor impairment

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17
Q

what happens when levels of serotonin and dopamine are increased

A

initially feel good feeling
dopamine breaks down

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18
Q

what happens when glutamate is decreased

A

impairs memory, judgement, thinking

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19
Q

more alcohol consumed, more effects on which system / brain area

A

limbic system
hippocampus is compromised

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20
Q

what happens when hippocampus is compromised

A

interferes with ability to form new memories (black outs)

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21
Q

what factors are related to BAC

A

amount ingested in period of time
empty vs full stomach
size of body
live efficiency
gender

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22
Q

acute withdrawal symptoms

A

physical - headache, nausea, tremors
psych - anxiety/depression symptoms

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23
Q

hard core withdrawal symptoms

A

organ failure
malnutrition
foetal alcohol syndrome
delirium tremens
- full body shakes and tremors
- hallucinations, can last up to 3 days

24
Q

nature of sedative drugs

A

calming

25
Q

nature of hypnotic drugs

A

sleep inducing

26
Q

nature of anxiolytic drugs

A

anxiety reducing

27
Q

rohypnol

A

date rape drug

28
Q

what receptors do depressants work on

A

GABA

29
Q

what does amphetamine use disorder produce and reudce

A

produces elation, confidence, vigour, increase heart rate
reduces fatigue, intestinal function, appetite

30
Q

what effects occur with larger doses of amphetamines

A

cross line into anxiety, agitation, nervousness

31
Q

what system to amphetamines stimulate and how

A

CNS
- increase dopamine, noradrenaline and serotonin

32
Q

what happens with too much dopamine released

A

results in tics

33
Q

what disorders occur with too little dopamine

A

parkinsons

34
Q

what does noradrenaline do

A

prepares body for fight or flight
increases heart rate
release glucose
moves blood away from digestive system to skeletal muscles

35
Q

effects of cocaine use

A

elation
vigour
reduced fatigue
dopaminergic

36
Q

what is vasoconstriction and what drug is it associated with

A

narrowing of blood vessels
cocaine

37
Q

effects of cannabis

A

euphoria
laughter
relaxation
happiness
appetite stimulation
paranoia
anxiety
delusions
hallucinations
STM impairment
pain relief
antiemetic (prevents vomiting)

38
Q

how does cannabis work

A

causes dopamine release
brains have endogenous cannabinoids - affect pleasure, memory, thinking, concentration, movement, coordination, sensory, time perception

39
Q

what is happening to the ratio of THC to CBD and what does this mean

A

THC is increasing (higher risk for negative symptoms)
cannabis is more potent

40
Q

cannabis use and SCZ

A

6x more likely to develop schizophrenia than non users

41
Q

effects of opiods

A

reduce pain
induce sleep
low doses - euphoria, drowsiness, slower breathing
higher doses - slows down functioning to extent it can be reversed

42
Q

how do opioids work as analgesics

A

similar to endorphines
reduce pain which is enduring

43
Q

concordance rates of SUDs

A

41-61% (identical twins)
24-42% (fraternal twins)

44
Q

genes identified with which substance abuse

A

smoking
alcohol

45
Q

neurobiology of drugs

A

affect pleasure pathway of brain

46
Q

drug users are more …

A

habit prone
compulsive

47
Q

social influences on drugs

A

family
peers
exposure

48
Q

pharmacological treatments

A

agonist substitution
antagonist treatment
aversive treatment

49
Q

agonist substitution

A

safe drug which similar chemical makeup
- but does not cause dependence or highs

50
Q

Antagonist treatment

A

dugs block effects of addictive drug
- unable to get positive effects

51
Q

Aversive treatment

A

drugs which make taking drug unpleasant
- has a high attrition rate

52
Q

psychosocial and cognitive intervention

A

confront sufferer and ask them to go to rehab

53
Q

community support programmes

A

learn to live with addiction

54
Q

contingency management

A

vouchers for good behaviour

55
Q

treatment - changes in use

A

controlled use vs complete abstinence

56
Q
A