Substance use and addiction disorders Flashcards
substance addiction
chronic medical condition rooted in environment, neuro, genetics, life exp
- strong sub craving
- desire to cut down w/o success
- can’t fulfill role obligations
- inc social iso sometimes
- hazardous activities
- continue despite potential harmful consequences
- excess time spent to get substances
- may cause tolerance or w/d
Biggest barrier to substance abuse
Stigma
- seen as moral weakness by many
Stigmatizing language
addict, alcoholic, drunk, sub/drug abuser, drug habit, drunk
countertransference
unconscious feel of HC worker to pt
- need to examine own perceptions toward addiction to dec bias and examine own attitudes
- often impairs the relx
Opioid epidemic
- 1st prescription opioids deaths (until 2010)
- then heroin OD (2013)
- synthetic opioid OD
Addiction rf
- genetic, males more but females faster
- NT w/ sub use dx—inc extracell Dp, immature brain dev
- enviro—stress, anx, sub use, use in fam/peers, lack coping
- starting alc, nic, drug use at an early age
- have other MH dx (self-medicate)
- higher among multiracial
Dopamine and addiction
- seek subs that release or inc release of DP in brain
- feel good NT
- inc extracellular Dp
Brain dev as rf for addiction
- early exp infl brain dev ( early trauma and stress chx)
- brain devs until 24 or later
- adol brain matures back to front
Decision making is more…
Frontal with adults and amygdala with teens
Alc cravings and acetate
- alc b/d to acetate (which triggers cravings for more)
- normal drinkers pass acetate thru quickly (panc and liver slower in addicts)
- in addicts, acetate does not process out so cont desire for more
- craving cycle
- acetate accum with 1 drink and does not change with ppl addicted
Neuro of tolerance
- from repeated use
- chx in NTs and dec D2r and dec dp release
- results in compulsive bx, dec inhib control, inc impulses, impair reg of intentional action
What other substance metabolizes into acetate
Nicotine - compounds effects
Substance intoxication
recent overuse of sub like acute alc intox casuing reversable substance-specific sx
- judgment impaired making maladaptive and inappropriate bx and impairing social and occupational functioning
- CNS chx
- alc: slur, poor coordination, stupor, dec memory
BAC legal intoxication
Over .08
Physical signs of alc intoxication
- muscle coord dec, hard to detect danger, judgment, memory impair
- driving - conc and memory dec, speed control, dec info process, impair perception
Tolerance
respond in diff way than initial drug response
- drink more for same response and diminished fxn with cont use
- rapid (coke) to w or m
Blackout
excess intake with amnesia
- may appear normal tho
relapse
drink after being abstinent for significant time beyond period of detox
Dual dx
AMI and sub/addictive use dx
substance w/d
- physio sx that occur when person stops using subs
- substance-specific
- more intense sx, more likely person is to start using subs again to avoid sx
Alcohol and BDZs timeline and w/d
- 6-12h mild insomnia, shaky, anx, GI, HA, diaphoretic, palpits, anorexia
- 12-24h halluc
- 24-48 w/d sz (t-c)
- 48-72h delirium tremens, halluc (mostly vis), tachy, low fever, agit, HTN, diaphoretic
- peak in 48h, over in 3-5d
How often to assess with CIWA
q4h
- assess n/v, tremor, anx, agit, paroxysmal sweats, orientation, HA, halluc/delusion
manage w/d of alc
- control agitate, dec sz, dec morb/mort
- may be fixed, schedules based on pt specific
- daily thiamine before IV dextrose to prevent Wernicke sx
- PRN for break thru
What meds are given for CIWA of 8-10+
chlordiazepoxide, diazepam, lorazepam