substance use Flashcards

1
Q

consumption amounts that increase the likelihood of health consequences

A

risky use

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2
Q

A state of adaptation that is manifested by a withdrawal syndrome that can be produced by abrupt cessation of a substance or by tolerance to the substance

A

physical dependence

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3
Q

A primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations.

A

addiction

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4
Q

use of any drug that deviates from approved social or medical patterns

A

abuse

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5
Q

applies to drugs that are prescribed by physicians and not used properly

A

misuse

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6
Q

Ability of one drug to be substituted for another producing the same effects physiologically and psychologically

A

cross tolerance

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7
Q

what is crucial to memory formation and gives motivation to repeat pleasurable experiences?

A

dopamine

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8
Q

dx for substance us include____for >____

A

clinical distress/impairment for >12 mon

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9
Q

4 categories defining substance use

A
  1. impaired control
  2. social impairment
  3. risky use
  4. pharmacological criteria
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10
Q

craving indicates____

A

impaired control

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11
Q

phamacoloical criteria include____ and ____

A

tolerance and withdrawal

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12
Q

which theory of alcohol use pathogenesis: direct activation of the reward centers

A

positive-affect regulation

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13
Q

which theory of alcohol use pathogenesis: self-medication

A

negative affect regulation

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14
Q

which theory of alcohol use pathogenesis: some people are just more prone to develop a use disorder

A

pharmacological vulnerability

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15
Q

which theory of alcohol use pathogenesis: alcohol consumption is part of an overall picture of social deviance arising in childhood and resulting from deficient socialization

A

deviance proneness

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16
Q

confusion + ataxia + ocular abnormalities

A

wernickes

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17
Q

alcohol is associated with what eye movement

A

nystagmus

18
Q

peak alcohol withdrawal occurs when?

A

48 hrs, can last 5 days

19
Q

clouding of sensorium, hallucinations, tachycardia, HTN , hyperthermia, diaphresis, asscd with alcohol

A

delirium tremens

20
Q

risk factors for delirium tremors (6)

A
  1. h/o sustained drinking
  2. h/x previous DT
  3. age >30
  4. concurrent illness
  5. significant alcohol withdrawl
  6. longer period since last drink
21
Q

what is CIWA

A

clinical institute withdrawal assessment – alcohol

22
Q

opioid antag used as maintenance tx for alcohol use disorder

A

naltrexone

23
Q

which drug used in alcohol use disorder works on GABA and glutamate?

A

acamprosate

24
Q

caffeine intoxication occurs at what level

A

> 250 mg

25
Q

caffeine withdrawal defined as ___sx within ___hours

A

3 sx within 24 hrs

26
Q

HA, fatigue, dysphoric, flue-like sx, difficulty concentating

A

caffeine withdrawl

27
Q

chronic weed use can lead to

A

amotivational syndrome

28
Q

K2 synthestic cannabinoid can induce____

A

psychosis

29
Q

which drug is NOT associated with withdrawal?

A

hallucinogens, inhalants

30
Q

nystagmus, dilated pupils, violent behavior, dissociative sx, HTN

A

phencyclidine

31
Q

what drugs are in the other hallucinogen use group

A

MDMA, mescaline, psilocybin, LSD

32
Q

COWS utilization

A

opioid withdrawal scale

33
Q

long-acting synthetic opioid agonist, Prevent withdrawal, Reduce cravings

A

methadone

34
Q

reduce or eliminate withdrawal symptoms associated with opioid dependence and carries a low risk of overdose.

A

buprenorphine

35
Q

opioid antag that prevents euphoric effects without any potential for abuse

A

naltrexone

36
Q

autonomic hyperactivity, hand tremor, hallucinations with reality intact

A

sedative/hyponotic/anxiolytic withdrawal

37
Q

what is a necessary criteria for definition of stimulant withdrawal?

A

dysphoric mood

38
Q

which substance is not related with intoxication?

A

tobacco

39
Q

short term residential tx typically lasts how long

A

3-6 week inpatient with extended outpatient tx

40
Q

long term residential care tx lasts how long

A

6-12 mon

41
Q

what test is used for confirmatory testing?

A

gas chromatography mass spec

42
Q

______are qualitative and gas chromatography is _____

A

qualitative; quantitative