depressive disorders Flashcards
most common conditions seen in primary care
- HTN
2. major depressive disorders
MDD definition: for at least _____, 5+ sx, at least one is_____or_____
for at least 2 weeks, 5+ sx, at least 1 is depressed mood or loss of interest/pleasure
anhedonia
loss of interest or pleasure in activities, most of the time, most days
are men or women at greater risk for experiencing a depressive disorder
Women
avg age of onset for mdd
mid 20’s
what predicts recurrence of depressive episodes?
residual sx
____who have a single major depressive episode never have another 1
40%
what percent of ppl with MDE will later have a manic episode
5-10%
most effective tx for MDD
psychopharmacology + psychotx
after starting anti-depressants, expect a ___% improvment within____
20% within 2 weeks
MAOi are known to interact with which common drugs (2)
- demerol
2. pseudoephedrine
vilazodone MOA
SSRI with 5HT binding properties
vortioxetine MOA
SSRI with multiple serotonin binding properties
compared to the general populaton, bipolar disorder has what relationship with risk of suicide?
incr risk (12-20% incr in risk)
mean age of onset for bipolar disorder
early 20’s
postpartum psychosis is considered a _____
manic episode
same sx as manic episode, but less severe, 4+ days
hypomanic episode (bipolar affective disorder type 2)
1+ manic or mixed episode
bipolar disorder type 1
1+ hypomanic and 1+ depressive episode without any manic episode
bipolar disorder type 2
depressive episode criteria for type 1 bipolar disorde
none required
2 years of fluctuating and depressive sx that don’t meet full criteria for a hypomanic or MDE
cyclothymia
common tx of bipolar disorder
lithium + antidepressant
