streptococcus pneumoniae

Question 1

1)Distinguish feature
2)virulence factor
3)Clinical manifestation
4)Predisposing factor
5)Prevention

Answer 1

1)gram+, catalase-,lancet-shape diplococci , encapsulated , a-hemolytic, optochin sensitive, bile soluble
2)capsule, IGA protease, Pneumolysin ,
3)MOPS
Meningitis(due to inflammation)
Otitis media-children
Pneumonia-elder(rusty-sputum)pericarditis
Sinusitis-sepsis in asplenic human
4)Drug, alcohol, neurogenic disease(lung function reduce), irritation, viral infection, CHF, sickle cell anemia(sepsis in this human)(asplenia), nephrosis, leakage of CSF in nose during trauma
5)IGM(unconjugated) in adult, IGG(conjugated) in childe