Mycoplasma pneumoniae

Question 1

1)General feature
2)transmission
3)Pathogenesis
4)Diseases
5)Diagnosis

Answer 1

1)extracellular, no cell wall, cholesterol in plasma membrane
2)close contacts of adult like military, college and other
3)Non invasive, P1 protein binds respiratory epithelium, inhibit ciliary movement, produce O2 free radicals and cytotoxin which damage respiratory cells, it is superantigen and cause cytokine storm and
than production of autoantibody
4)atypical pneumonia, bronchitis and extrapulmonary manifestation(due to autoantibody)
5)reticulonodular picture on x-ray and IgM cold agglutination of RBC