staphylococcus aureus

Question 1

1)General feature
2)inflammatory mediated disease
3)Toxin mediated disease
4)Explanation of MRSA

Answer 1

1)Gram+, catalase+, coagulate+, B-hemolytic, colonize skin, protein A (antiphagocytic activity)
2)pneumonia(superinfection), skin abscesses, septic arthritis, acute endocarditis(tricuspid valve damage IV drug users), osteomyelitis.(leukocidin may take part in this processes, it is cytotoxin which make pores to damage cell)
3)TSS- superantigen leads to cytokine storm
scalded skin syndrome(exfoliative -damage intercellular contacts)
food poisoning- enterotoxins
4)Due to altered PBP