Legionella

Question 1

1)important properties
2)Transmission
3)Predisposing factor
4)Pathogenesis and disease

Answer 1

1)gram - rod ( silver stein), iron and cysteine containing charcoal yeast , in water sources
2)No human to human transmission , air conditioner and hospital water sources
3)age >55 and smoking with alcohol intake also immunosuppressed
4)facultative intracellular and has endotoxin and damage endothelium of brain and kidney capillary , cause legionella disease with atypical pneumonia, hyponatremia, confusion with headache, microscopic hematuria and proteinuria, diarrhea and fever. It also cause Pontiac fever- self-limited mild flue-like symptoms