Streptococci

Question 1

Alpha, beta, and gamma `

Answer 1

Alpha - mutans and pneumo
Beta - pyo and GBS
Gamma - enterococcus

Question 2

Strep pyo

Answer 2

Causes pharyngitis…usually self-limiting without TX

Question 3

Mechanism of virulence factors of group A strep

Answer 3

Hyaluronan capsule uses mimicry
Protein F adheres to fibronectin
M protein is antiphago
Streptokinase dissolves clots 
Streptolysin induce leukocyte and RBS lysis

Question 4

Erysipelas

Answer 4

Caused by S pyogenes…spreads into lymph nodes.triggering pain and inflammation…caused by different M group strep than

Question 5

Erysipelas diagnosis

Answer 5

Reddening of skin of the face, arms, legs, red area has margin

Question 6

Mech of erysipelas

Answer 6

Pyrogenic toxins stimulate macos and help T lymphos release cytokines

Question 7

Rheumatic fever

Answer 7

Inflamm dz caused by antigenic similarity between M protein and myosin

Question 8

Necrotizing fasciitis

Answer 8

Pain is not proportionate to appearance

Fever, nausea and low BP if deeper

Strep enters and spreads rapidly…secretes enzymes that destroy tissues…skin becomes distended and discolored

Question 9

GBS

Answer 9

Transmitted mother to infant and causes neonatal meningitis

Antiphagocytic sialic acid capsule is the key to infection here

High mortality

Question 10

Strep pneumo

Answer 10

Polysac capsule inhibits C3b deposition
Pili adheres
Pneumolysin destroys PMNs
IgA protease

Causes ear infections, otitis media, meningitis

Question 11

Prevention of strep pneumo

Answer 11

Pneumococcal polyssach - 23 serotpyes used for older than 2 y/oi

Pneumococcal conjugate - polyvalent

Question 12

Strpe mutans

Answer 12

Dental caries…ferments sugars to acid that dissolve enamel