Bacterial Toxins Flashcards
1
Q
Faciliate Spread
A
Hyalurodinase and collagenase break down host tissue and allow invasion
2
Q
Damage membranes
A
PVL from S aureus that pokes holes in neutrophils
3
Q
Stimulate cytokine production
A
Superantigens (s aureus)
4
Q
A-B toxin
A
B toxin responsible for binding…receptor mediated endocytosis and acidification causes release of A subunit that is active
5
Q
Example of AB toxin
A
Exotoxin A from pseudomonas
6
Q
Inhibit protein synthesis
A
Exotoxin A and shiga toxin
7
Q
Activate 2ndary messenger paths
A
Cholera toxins activate adenylate cyclase
8
Q
Nihibit NTs
A
Clostridium botulinum and tetanus