Strep

Question 1

Lancefield Typing

Answer 1

Typing of C carbohydrate

Types A-O

Question 2

Nutritionally Variant Strep

Answer 2

“Abiotrophia”

Pyridoxial-dependent Strep require Vitamin B6 (pyridoxial hydrochloride) for growth

NVS satellite around E.coli, Staph, Klebsiella, yeast, Enterobacter

(Should be suspected in blood cultures are positive, but sub cultures are negative

Question 3

Pharyngitis

Answer 3

sore throat, fever, exudate

NO cough/runny nose

Question 4

Scarlet Fever

Answer 4

Scarlet Fever Toxin
Pharyngitis with rash
Strawberry Tongue (red with white pillae)

Question 5

Impetigo

Answer 5

kids
lesions/pustules
treated with Pen

Question 6

Erysipelas

Answer 6

follows strep throat

raised demarkated margin, confined to face

Question 7

puerperal sepsis

Answer 7

women following child birth

bug invades genital tract -> endometriosis, bacteremia, TSS, necrotizing fascitis

Question 8

Acute Rheumatic Fever (ARF)

Answer 8

Kids 6-15 yo, 2-5 weeks post Strep Throat
Inflammatory lesions involving heart, joints, tissue, CNS
“Polyarthritis”: migratory, multiple joints
Endocarditis, myocarditis, pericarditis

Lab Findings:
increased CRP, Increased ASO, Increased ESR
Increased Anti-DNAse, Anti-hyaluronidase

Associated with large amounts of M protein and capsule

Question 9

Acute Glomerulonephritis (AGN)

Answer 9

Inflammation of renal glomerulus
10days-6 weeks post infection
Edema, hyertension, dark urine, hematuria, proteinuria

Lab Findings:
Increased ESR, Anemia
Increased Anti-DNAse, Anti-hyaluronidase
NO increase in ASO

Question 10

Strep agalactiae

Answer 10

Screening at 35-37 weeks
CAMP test + (produces CAMP factor, Staph must produce beta-lysin)
Bacitracin Resistant

Question 11

Enterococcus faecalis

Answer 11

UTI, wounds, abscesses
Resistant to Beta-lactams and aminoglycosides

Enterococcus is Bile Esculin +

Question 12

Strep mutans

Answer 12

tooth decay

Question 13

Strep pneumoniae

Answer 13

virulence = capsule
Pneumonia, otitis media, bacteremia

TX: Pen, Erythro, chloramphenoicol

Question 14

Strep Pathogenicity- Hemolysins

Answer 14

SLS: Strep A, C, G (causes beta-hemolysis); lyses RBCs after binding to membrane

SLO: Supresses chemotaxis, neutrophils, inhibits phaygocytosis, oxygen labile

Question 15

ASO TEST

Answer 15

Measures Anti-SLO to see if there was a recent Strep. pyogenes infection

Question 16

Strep Pathogenicty- M Protein

Answer 16

Part of the cell wall, inhibits phaygocytosis

M Protein types 1 and 3 = TSS

Question 17

Group C Strep

Answer 17

Strep. equisimillis
Strep. equi
Strep. zooepidermicus
Strep. bovis
Strep. equinis

Question 18

Aerococcus

Answer 18

GPC clusters

grows in NaCl

Question 19

Strep pyogenes

Answer 19

Bacitractin susceptible