Stomach Flashcards
Rugae
Located on mucosal layer
Large, longitudinal folds
Allow the stomach to expand when needed
Main function
Food storage and digestion
Chyme
Chemical breakdown of food
Bolus –> becomes chyme in the stomach
Cardia
Small
1st top/part
Surrounds cardial orifice (through which food enters the stomach from the esophagus)
Fundus
Stomach’s dome-shaped part
Beneath diaphragm and bulges above the cardia
Body
Mid-portion
Continuous with pyloric part
Pyloric region
Terminal part that meets duodenum
Pyloric sphincter: separates stomach from small intestine; controls stomach emptying
Mucous neck cells
Secrete mucus
Parietal cells
Secrete HCl and IF
HCl: needed for activation of pepsin
IF: intrinsic factor; needed to absorb B-12 vitamin in the small intestine
Chief cells
Secrete pepsinogen (inactive pro-enzyme of pepsin) Secrete lipases
Pepsin
1 digestive protein enzyme in the stomach
Enteroendocrine cells
Secrete chemical messengers directly into interstitial fluid of lamina propria D cells G cells Enterochromaffin cell Enterochromaffin-like cells
D cells
Secrete somatostatin (inhibitor)
G cells
Secrete gastrin (stimulatory; excites parietal cells)
Enterochromaffin cells
Secrete serotonin (excites smooth muscles to contract)