Stimulants

Question 1

what do stimulants increase?

Answer 1

alertness
wakefulness
energy
alertness

Question 2

prescribed stimulants are what class of drugs according to government? how must they be prescribeD?

Answer 2

class 2 must be prescribed electronically and no refills

Question 3

methylphenidates and amphetamines have the same goal of doing whta?

Answer 3

increasing dopamine and NE

Question 4

how do methylphenidates increase dopamine and NE?

Answer 4

block the NETransporter and DATransporter molecules that usually decrease the extracellular amount of these

Question 5

how do amphetamines increase dopamine and NE? where do they increasE?

Answer 5

dose dependent increase..dopamine increases in the striatum and NE in the prefrontal cortex

Question 6

order the potency of amphetamines/methylphenidates, caffeine, and crystal methamphetamine

Answer 6

Highest-crystal meth
middle- amphetamine/methylphenidate
low-caffeine

Question 7

name four pediatric indications for for stimulants

Answer 7

ADHD
CD
ODD
ASD

Question 8

name three adult stimulant indications

Answer 8

ADHD
binge eating
narcolepsy

Question 9

name four adverse effects of stimulants

Answer 9

weight.growth deficit
headache/GI transient effect
Tics
Arrhythmias

Question 10

what is the autonomic nervous system class of drugs that can be used for stimulant?

Answer 10

alpha 2 agonists

Question 11

name the alpha 2 agonists used for stimulant therapy?

Answer 11

clonidine and guanficine

Question 12

why do alpha 2 agonists work for stimulant therapy?

Answer 12

mimic effect of NE

Question 13

which of the alph 2 agonists has a short half life? what is the issue associated with this?

Answer 13

clonidine…higher rates of rebound HTN

Question 14

what are SEs of alpha 2 agonists used as stimulants?

Answer 14

hypotension
dry mouth
headache
fatigue

Question 15

aside from ADHD, where else can clonidine and guanfacine be used?

Answer 15

opioid withdrawal
PTSD
impulsivity

Question 16

what is the MOA of atomoxetine?

Answer 16

norepinephrine reuptake inhibitor…no dopamine effect

Question 17

what is the stimulant that isnt an amphetamine or methylphenidate that takes 2-3 weeks to begin acting?

Answer 17

atomoxetine

Question 18

what is MOA of bupropion?

Answer 18

selectively inhibits uptake of dopamine and NE…has amphetamine like structure

Question 19

what is stimulant that should only be given in AM?

Answer 19

bupropion

Question 20

when should you def not give bupropion?

Answer 20

if patient has seizure disorder, prior diagnosis of bulimia or anorexia nervosa, or patients discontinuing alcohol/sedative use