Mood Disorders Flashcards

1
Q

how long must you have symptoms to be diagnosed with MDD?

A

2 weeks

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2
Q

how many symptoms must you have to have MDD?

A

5…

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3
Q

what are the symptoms of MDD?

A
low mood
weight loss or gain
fatiigue
poor concentration
worthlesness/guilt
insomnia/hypersomnia
suicidal ideation
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4
Q

what is the mnemonic for depressive symptoms?

A

Sleep disturbance
Iinterest/pleasure reduction
Guilt

Energy loss

Concentration impairment
Appetite changes
Psychomotor changes
Suicidal thoughts

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5
Q

name five predisposing environmental factors for mood disorder

A
low birth weight 
childhood illness/abuse 
unemployment
loss of parent 
social isolation
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6
Q

what is the NT change in depression

A

decrease in dopamine, NE and serotonin

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7
Q

what is the NT change in Mania?

A

increase in dopamine, decrease in GABA

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8
Q

what is the NT change in schizophrenia?

A

increase dopamine and serotonin

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9
Q

what is the NT change in anxiety?

A

decrease GABA and serotonin, increase NE

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10
Q

what is the median duration of MDD?

A

20 weeks

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11
Q

what are sleep changes associated with MDD?

A

difficulty initiating, maintaining sleep or too much sleep

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12
Q

what are EEG changes to sleep with MDD?

A

very little slow wave sleep, longer REM sleep

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13
Q

what is the mnemonic for risk factors for depression?

A

SADPERSONS

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14
Q

what does the S stand for in SADPERSONS?

A

Sex…male

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15
Q

what does the A stand for in SADPERSONS?

A

Age less than 18 and more than 45

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16
Q

what does the D stand for in SADPERSONS?

A

Depression

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17
Q

what does the P stand for in SADPERSONS?

A

Past attempt

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18
Q

what does the E stand for in SADPERSONS?

A

Etoh or illicit substances

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19
Q

what does the R stand for in SADPERSONS?

A

rational thinking loss

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20
Q

what does the S stand for in SADPERSONS?

A

SIngle, widowed, divorced

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21
Q

what does the O stand for in SADPERSONS?

A

Organized plan

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22
Q

what does the N stand for in SADPERSONS?

A

No social support

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23
Q

what does the S stand for in SADPERSONS?

A

Stated intent

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24
Q

what is it called when a mood disorder starts due to substance use?

A

substance induces mood disorder

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25
Q

do Benzos cause depression or mania?

A

depression

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26
Q

do alcohol cause depression or mania?

A

depression

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27
Q

do interferon-alpha cause depression or mania?

A

depression

28
Q

do corticosteroids cause depression or mania?

A

both

29
Q

what are the diagnostic criteria for Bipolar I disorder?

A
one week of elevated expansive or irritable mood with increased activity energy
with 
three of these: increased self esteem
decreased need for sleep
increased talking
racing thoughts
distractible
30
Q

what is the mnemonic for Bipolar I symptoms?

A

Distracible
Impulsive
Grandiosity

Flight of ideas
Activity increased
Sleep decreased
Talkativeness

31
Q

what is the difficulty with diagnosing bipolar I disorder?

A

over 50% of patients present in depressed mood on first visit

32
Q

in addition to a manic episode what must you have for bipolar I?

A

depressive episode

33
Q

what is diagnostic criteria for bipolar II disorder?

A

Major depressive episode and hypomania…no manic episode allowed

34
Q

what other psych illness is bipolar II disorder associated with most commonly?

A

anxiety

35
Q

what are people with bipolar at a really elevated risk for compared to general population?

A

SUICIDE

36
Q

when do mood disorders lead to psychotic features?

A

only at the highest and lowest points…major depressive and manic episodes

37
Q

what is the diagnostic criteria for PDD?

A

less symptoms and milder than MDD..but chronic depressive symtpoms

38
Q

is PDD worse or better with symptoms that MDD?

A

it is not as bad

39
Q

what is double depression?

A

when a patient with PDD develops a major depressive episode…84% risk of this happening with PDD

40
Q

what is Rx for double depression and PDD?

A

antidepressants and psychotherapy

41
Q

what is cyclothymia?

A

changes between levels of hypomania and and periods of depressive symptoms

42
Q

how long does cyclothymia have to last?

A

for at least 2 years

43
Q

what is bipolar NOS?

A

rapid alterations between manic symptoms and depressive symptoms that meet symptom threshold criteria but not duration for manic, hypomanic, or major depressive episodes

44
Q

why is bipolar NOS not able to be considered a manic, hypomanic or major depressive episode?

A

it is short lasting…like a couple days

45
Q

what is the therapy for seasonal affective disorder?

A

light therapy

46
Q

what is mood reactivity in atypical depression?

A

they are able to respond with better mood to positive events

47
Q

what are the reversed vegetative symptoms in atypical depression?

A

hypersomnia and hyperphagia

48
Q

does normal depression feel worse at night or in the morning?

A

in the morning for normal

49
Q

doe atypical depression feel worse at night or in the morning?

A

at night for atypical

50
Q

what can PPD cause between mother and child?

A

difficulty in bonding in the early years…this can lead to negatively impact of a childs emotional and cognitive development

51
Q

what does the presence of PPD have an odd assocations?

A

PTSD and trauma

52
Q

what are risk factors for PPD during pregnancy>

A

stressful life event, depression/anxiety symptoms and inadequate social support

53
Q

what is a biological issue that causes risk for PPD?

A

thyroid dysfunction

54
Q

what is the risk factor for age with PPD?

A

age under 18 yo

55
Q

what is risk factor for breastfeeding with PPD?

A

early weening of breastfeeding

56
Q

what are the postpartum blues?

A

2-3 days of more crying emotional liability and irritability, less sleep and appetite disturbances

57
Q

when does postpartum blues occur? how long does it last?

A

2-3 days after birth and lasts 2-3 days

58
Q

what is postpartum blues due to?

A

abrupt hormone withdrawal…progesterone gone

59
Q

what is diagnostic criteria for PPD?

A

same as MDD but must be within first month post delivery

60
Q

what is Rx for PPD?

A

antidepressants and CBT

61
Q

is the HPA axis over or underreactive during pregnancy?

A

overreactive

62
Q

is the HPA axis over or under active during postpartum and PPD?

A

under active

63
Q

what is postpartum psychosis?

A

2-4 weeks post delivery…confused thinking, mood swings, delusions, paranoia poor judgement and impaired functioning

64
Q

how soon does postpartum psychosis occur?

A

2-4 weeks post delivery

65
Q

who is postpartum psychosis most common in?

A

mothers with bipolar disorder