Step1_DEMS Flashcards

1
Q

What type of lung cancer is ~w/ PTH-related peptide, that causes para-neoplastic hypercalcemia?

A

Squamous Cell lung cancer

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2
Q

______________ is an AI disease that is characterized by T-lymphocyte-meditated destruction of intra-LOBULAR bile ducts.

A

Primary Biliary Cholangitis (PBC).

The destruction of bile ducts results in the toxic accumulation of hydrophobic bile acids (e.g. cholic acid, chenodeoxycholic acid, deoxycholic acid), which act as detergents to disrupt cell membranes, thereby exacerbating the inflammatory process.

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3
Q

Patients with a history of celiac disease are at increased risk of developing what disease process?

A

malignancy, specifically lymphoma of the small bowel.

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4
Q

Patients with _________ are also predisposed to developing other gastrointestinal cancers, such as esophageal squamous cell carcinoma, intestinal adenocarcinoma, colorectal carcinoma, and hepatocellular carcinoma.

A

celiac disease

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5
Q

What type of pancreatic cytsts account for approximately 75% of all cysts in the pancreas and consist of local collections of hemorrhagic-necrotic cellular material filled with pancreatic enzymes. They are formed by the walling-off of regions of hemorrhagic fat necrosis. They lack a true epithelial lining, but instead are lined by fibrous and granulation tissue.

A

Pseudocysts

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6
Q

What is a common complication of acute pancreatitis?

A

Pancreatic Pseudocysts.

can also occur 2/2 to chronic alcoholic pancreatitis

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