Stem cells HSCs and MSCs

Question 1

In which body cells do stem cell s exist (8)

Answer 1

bone marrow, brain, skin, fat, muscle, bone, blood, intestine

Question 2

HSCs are derived from

Answer 2

blood stem cells

Question 3

blood stem cells split into (2)

Answer 3

myeloid stem cells and lymphoid stem cells

Question 4

Myeloid stem cells split into (3)

Answer 4

red blood cells, platelets, myeloblast

Question 5

lymphoid stem cell

Answer 5

lymphoblast

Question 6

what forms white blood cells (2)

Answer 6

myeloblasts and lymphoblasts

Question 7

where are GI stem cells located

Answer 7

crypt

Question 8

what are GI stem cells associated with (2)

Answer 8

paneth cells and TA cells

Question 9

Where are MSCs from

Answer 9

Bone marrow

Question 10

MSC property

Answer 10

self renewal

Question 11

MSCs can differentiate into what in vitro (3)

Answer 11

adipocytes, chondrocytes, osteocytes

Question 12

adipocytes

Answer 12

fat cells

Question 13

chondrocytes

Answer 13

cartilage cells

Question 14

osteocytes

Answer 14

bone cells

Question 15

cells that can become a new individual with maternal support

Answer 15

totipotent

Question 16

cells that he can become any adult tissue cells

Answer 16

pluipotent

Question 17

cells that can become several types of mature cells

Answer 17

multipotent

Question 18

zygotes are

Answer 18

totipotent

Question 19

embryonic stem cells and iPSC are

Answer 19

pluripotent

Question 20

iPSC

Answer 20

induced pluripotent stem cells

Question 21

tissue stem cells are

Answer 21

multipotent

Question 22

pluripotent stem cells can differentiate into (2)

Answer 22

HSCs and MSCs

Question 23

HSC

Answer 23

haematopoietic stem cell

Question 24

MSC

Answer 24

mesenchymal stem cell

Question 25

MSCs can differentiate into (2)

Answer 25

fibroblasts and adipocytes

Question 26

HSCs can differentiate into (2)

Answer 26

B cells and macrophages

Question 27

what is it called when B cells differentiate into macrophages

Answer 27

transdifferentiation

Question 28

what is blood

Answer 28

fluid connective tissue

Question 29

Blood functions (7)

Answer 29

oxygen transport, nutrient transport, ormone transport, heat regulation, immune system, haemostasis, waste product removal

Question 30

haemostasis

Answer 30

clotting

Question 31

WW2

Answer 31

1939-45

Question 32

when was fear and interest in radiation therapies heightened (2)

Answer 32

post WW2 and cold war

Question 33

what treatments for cancers emerged (2)

Answer 33

radiotherapy and chemotherapy

Question 34

which elements of blood continuously renew (4)

Answer 34

granulocytes, erythrocytes, lymphocytes, platelets

Question 35

blood before centrifuge (2)

Answer 35

diluted peripheral blood and separation medium

Question 36

blood centrifuge for separation

Answer 36

2200 rpm 30 min

Question 37

blood centrifuge elements (3)

Answer 37

55% plasma, 1% platelets and PBMCs, 45% RBCs and polymorphonuclear cells

Question 38

PBMC

Answer 38

peripheral blood mononuclear cells

Question 39

plasma elements (4)

Answer 39

cytokines, water, proteins, electrolytes