Metabolic Syndrome Prevention and Treatment Flashcards

1
Q

VLDL triglyceride surface markers (3)

A

CII, CIII, B300

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2
Q

cholesterol change in MetSys (2)

A

decreased HDL and increased LDL

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3
Q

what does triglyceride deposition in muscles lead to

A

insulin resistance

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4
Q

what does excess visceral fat release

A

cytokines

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5
Q

cytokine release leads to (3)

A

increased insulin resistance, fat cell lypolysis, free fatty acid secretion

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6
Q

liver produces (4)

A

C reactive protein, VLDL, fibrinogen, glucose

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7
Q

fibrinogen produces

A

prothrombic state

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8
Q

adipose tissue produces (4)

A

free fatty acids, PAI 1, TNFalpha, IL6

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9
Q

PAI1

A

plasminogen activator inhibitor 1

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10
Q

IL6

A

interleukin 6

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11
Q

adipose tissue inhibits

A

adiponectin

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12
Q

cytokines act on (2)

A

adipose tissue and liver

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13
Q

cytokines inhibit

A

blood insulin uptake

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14
Q

Free fatty acids promote

A

blood triglyceride uptake

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15
Q

free fatty acids inhibit

A

blood insulin uptake

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16
Q

adipose tissue elements on blood vessels (4)

A

increase PAI1, increase adipokines, increase FFA, decrease adiponectin

17
Q

adipose tissue affect on blood vessels

A

increased endothelial dysfunction

18
Q

adipose tissue elements on RBC

A

adipokines

19
Q

adipose tissue affect on RBC

A

increased monocyte inflammatory gene expression

20
Q

adipose tissue elements on liver (2)

A

increased adipokines and free fatty acids

21
Q

adipose tissue affect on liver

A

nonalcoholic steatoheaptitis

22
Q
A