Stem cells and differeniation Flashcards

1
Q

Enthrocytes

A

Flattened biconcave shape - increases SA:V ratio, maximising the oxygen absorption - quicK diffusion rate

No nuclei - more space for haemoglobin

Flexible - to fit through narrow capillaries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Neutrophils

A

Part of immune response

Multi lobed nucleus- for squeezing through small gaps to get to site of infection

Granular cytoplasm - Contains lysosomes that conrain enzymes used to attack pathogens

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sperm cell

A

Male gamete
Tail/ flagellum - capable of movement

Lots of mitachondria/ enzymes - supply energy to swim

Acrosome on head- digestive enzymes are released to digest protective layers around the ovum and allow spleen to penetrate - fertilisation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

palisade

A

Found in mesophyll

  • chloroplasts ABSORB large amounts for photosytnethsis
  • cells CLOSELY slacked to form a continuous layer

THIN walls increase diffusion rate of CO2

Large vacuole to maintain turgor pressure

Chloroplasts move within cytoplasm in order to absorb more light

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Root hair cells

A

Surfaces of roots near growing tips

  • long hair liek extensions called Root hair cells which I crease the surface area of cell

This MAXIMISES uptake

Lots of mitachondria which provide more energy for active transport

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

GUARD cells

A

Form small opening called stomata

Needed for co2 to enter plants for photosynthesis

Loosing h20 causes them to become LESS swollen as a result of osmotic forces - change shape and stoma closes to prevent further loss

Cell wall - thicker on ONE side

Cell doesn’t change shape symmetrically as it’s volume changes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is a tissue

A

A tissue is made of a collection of diffferentiated cells that have a specialised function/s

As a result each tissue is adapted for a particular function within the organism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

4 main categories of tissues in animals

A

Nervous tissue
Epithelial tissue
Muscle tissue
Connective tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Nervous tissue

A

Adapted to support the transmission of electrical impulses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Epithelial tissue

A

Adapted to cover body surfaces, internal and external

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Muscle tissue

A

Adapted to contract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Connective tissue

A

Adapted to either to hold other tissue together as as a transport system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Squamous epithelium

A

Made up of specialised squamous epithelial cells, sometimes lnown as a PAVEMENT epithelial due to flat appearance

Very THIN due to squat/ cells that make it up and only one cell thick

Present when rapid diffusion across a surface is essential

Forms lining of lungs and allows RAPID diffusion of oxygen into the blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Ciliated epithelium

A

Made up of ciliated epithelial cells
Hair like structure called CILIA on one side - move in RHYMIC manner
Lines tranchea causes mucus to be swept away by the lungs
Goblet cells RELEASE mucus to trap unwanted particles present in the air , preventing particles which may be bacteria from reaching alveoli once inside the lungs
Microtubules - 9+2 arrangement
Fallopian tubes
Mobile or stationary e.g. sensory organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Muscle

A

Needs to be able to contact in order to move bones which In turn move the different part of the body

Different types of muscle fibres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Smooth muscle

A

Inability to control their movement

HOLLOW organ e.g. uterus and stomach

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Skeletal muscle

A

Attach to bones and have the main function of contracting to facilitate movement of our skeleton

Contain microtubules which contain contractile proteins

18
Q

Cardiac muscle

A

High contractile strength

SOLELY in the walls of the heart

Similarities to skeletal muscles in that is stimulated and smooth muscles in that is contraction are NOT under contious control

19
Q

Epidermis

A

Single layer of closely packed cells covering surfaces of plants

Covered by wa y cuticle( waterproof)to prevent loss of water

Stomata- formed by a pair of guard cells that open and close

Allow CO2, O2 and water vapour in and out

Short distance so light can penetrate - 1 cell thick, transparent

Protective barrier agianstpp

20
Q

Xylem tissue

A

Type of vascular tissue responsible for the transport do water and minerals

Tissue is composed of vessel elements which are composed of vessel elements - ELONGATED dead cells

Walls of these cells are strengthened with a waterproof material called lignin, which provides structural supporT
NON living

Pits - allow water to leave xylem to get to shoots

21
Q

Phloem

A

Type of vascular tissue

Responsible for transport of organic nutrients particularly sucrose from leaves and stems where it’s made

Composed of volume of sieve tube cels Seperated by perforated walls called sieve plates

Connected to companion cells - ATP for active transport

No nucleus - more space

Both directions

Parenchyma - store food and release chemicals do not eaten by herbivores

22
Q

Organs

A

Collection of tissues that are adapted to perform a particular function in an organism

23
Q

Organ systems

A

Large multicellular organisms have coordinated organ systems

Each organ system is composed of a number of Organs working together to carry out a major function in the body

24
Q

What are stem cells

A

Able to undergo cell division again and again and are the source of new cells necessary for growth development and tissue repair

Once stem cells become specialised they loose the ability to divide entering the g 0 phase if the cell cycle

Activity do stem cells has to be strictly controlled

25
Stem cell potency
Ability to differentiate The greater the number of cell types it can differentiate into the greater the potency
26
Totipotent stem cells
Can differentiate into ANY type of cell Fertilised egg, zygote and the 6 or 16 cells from its first miotic divisions are TOTPOTENT Destined to eventually produce a whole organism They can also differentiate into extra-embryonic tissues liek the Anouium and umbilicus Differentiate into cells which produce the embryo and placenta
27
Pluripotent cells
Can form ALL tissue types but not whole organisms | Present in early embryos and are the origin of the different types of tissues within an organism
28
Multi potent
The stem cell can only form a range of cells within a certain types of tissue Haemotopeitic cells in bone marrow are multi potent because this gives rise to various types of blood cell
29
Sources of plant stem cells
Meristems/meristematic tissue Found where growth occurs in a plant E.g. Tips of roots and shoots Meristematic tissue can be found between phloem and xylem tissue(vascular cambium) Cells found here will DIFFERENTIATE into cells found in xylem and phloem this allows vascular tissue to grow as the plant grows, the pluripotent nature of stem cells in meristem occurs throughout WHOLE life of plant
30
Sources of animal stem cells - embryonic stem cells
An embryo develops from a fertilised egg All the cells in an embryo start off identical and undifferentiated - they are embryonic stem cells (TOTPOTENT)
31
When do embryonic stem cells change to pluripotent state
They can become specialised to form any type of cell by switching gens on and off Whole new organism develops form embyronic stem cells After 7 days the mass of cells, BLASTOCYST, it's in its pluripotent state- remain in this state until birth
32
Adult stem cell - sources of animal stem cells
Some stem cells remain in the body of adults , found in limited numbers at certain locations Can differentiated into related cell types ONLY E.g. Bone marrow - can only differentiate into blood cells adn cells of immune system Multi potent, but evidence they can artificially be triggered to be PLURIPOTENT Can be harvested from umbilical cord ( blood stem cells )
33
Where can adult stem cells be found
Brain, eyes, blood,heart, liver, bone marrow, skin, muscle
34
What is differentiation
The process of a unspecialised cell becoming specialised and having a specific function
35
Replacement of red blood cells
Erythrocytes are ESSENTIAL for oxygen transport Due to lack of nucleus and organelles - live for only 120 days Need replacing constantly Stem cell colonies in the bond marrow produce 3 billion per kg of body mass per day
36
Replacement of white blood cells
Neutrophils Essential role in immune system Live for around 6 hours and the colonies of bone marrow produce 1.6 billion per kg per HOUR Figure increases during infection
37
Ethics - stem cells
Removal of stem cells from embryos - destruction, live begins at contraception - MURDER Possibly having another child just so they can use the umbilical cord for stem cells Adult stem cells- don't divide as well and are likely to get a mutation Test on rats adn animals- give them treatments developed by stem cells
38
Uses of stem cells examples?
Heart disease - muscle tissue in heart damaged aw a result of heart attack Type 1 diabetes - pluripotent stem cells to produce glucose responding cells that RELEASE INSULIN Parkinson's Birth defects Macular disease Alzheimer's Drug trails Development biology Burns Spinal injuries -stem cells to repair spinal cord- repair nerve ends
39
Stem cells - Alzheimer's
Transplanting neurall stem cells into brain of mice = POSITIVE EFFECT Build up of abnormal proteins
40
Burns - stem cells
Stem cell grown on biodegradable meshes can produce new skin for burn patients- quicker than Normal process of taking grade from at other part of the body
41
Development biology - stem cells
With their ability to divide indefinitely, and differentiate Study of changes that occur as multicellular organisms grow and develop from single cell and why things go wrong