STD - Chlamydia trachomatis

Question 1

Morphology

Answer 1

gram negative bacilli

Question 2

Classification/Diagnosis

Answer 2

Grows on living cells/tissues only
test by nucleic acid amplification tests 
Serotypes 
A-C (trachoma in the eye)
D-K (urogenital)
L1-L3 (lymphogranuloma venereum)

Question 3

Pathology

Answer 3

obligate intracellular pathogen
infectious elementary body enters cells, replicates as reticulate body, destroys host cells, stimulates inflammatory response

No lasting immunity

Question 4

Epidemiology

Answer 4

Direct mucosal contact with infected membranes of fluids
Congenital
most commonly reported infectious disease in US, 4 million new cases/year
Adolescents at high risk

Question 5

Diseases/Symptoms

Answer 5

Same as gonnorrhea minus pharyngitis/DGI and plus neonantal syndrome
Chronic infection is asymptomatic and causes tubal infertility
lymphogranuloma venereum (inguinal lymphadneopathy, proctitis, fever, tenesmus, bleeding, rectal pain)

Question 6

Treatment/Vaccination

Answer 6

Single-dose azithromycin or 7-day regimen of doxycycline

screening is essential