GI (non-diarrheal) - Helicobacter pylori Flashcards
1
Q
Morphology
A
Gram Negative
Curved Rod
Flagella
Motile
2
Q
Classification/Diagnosis
A
test by microscopy of biopsy
urease-breath test
detection of host antibodies
3
Q
Pathology
A
Survives in acid of stomach, chronic inflammation, increased gastric acid, CagA inhibits clearance, VacA erodes gastric epithelia
4
Q
Epidemiology
A
person-person spread, oral-fecal route
infection increases with age, correlates to socioeconomic status
5
Q
Diseases/Symptoms
A
All symptoms in upper GI tract, gastritis, gastric and duodenal ulcers, gastric adenocarcinoma
6
Q
Treatment/Vaccination
A
combination therapy of multiple antibiotics and proton pump inhibitor
