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PoD 2 > Staphylococci > Flashcards

Staphylococci Flashcards

1
Q

The only one that is Coagulase +

A

S. Aureus

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2
Q

CNS

A

S. Epidermis

S. Saprophyticus

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3
Q

Capsule

A

Helps in
Adherence
Inhibiting chemotaxis, phagocytosis

Imp for coagulase negative strains

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4
Q

Enzymes

A

Lipase

Hyluronidase

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5
Q

Location of methicillin resistance gene

A

MecA gene on staphylococcal cassette chromosome (SCCmec)

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6
Q

Protein A

A

S. Aureus

Covalently linked with peptidoglycan layer
Binds Fc portion of IgG

Opsonization and phagocytosis (protection)

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7
Q

Coagulase

A

Clumping factor

Fibrinogen to fibrin

Protects bacteria under fibrin mash

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8
Q

Staph toxins that are Superantigens

A

Exfoliative toxin A
Enterotoxins
TSST-1

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9
Q

Panton Valentine leukocidin

A

Makes s. Aureus more resistant to phagocytosis

Agains PMN and Macs

MRSA –> airway bleeding , erythroderma, leucopenia

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10
Q

Ritter’s Disease

Staph scalded skin syndrome

A

Positive Nikolsky’s sign

Entire body

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11
Q

Nikolsky’s sign

A

Large blister with clear fluid

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12
Q

What does exofoliative toxin destroy

A

Intracellular connections in the skin

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13
Q

Bullous impetigo

A

Localized staph scalded skin syndrome

No Nikolsky’s sign

Highly communicable

Culture positive

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14
Q

Pustular impetigo

A

Pus filled vesicles

Crusted lesions

S. Aureus or SA + GAS

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15
Q

TSS

A

Cutaneous and soft tissue involvement

Tampons

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16
Q

Food poisoning

Enterotoxin

A 
Mean incubation - 4 hrs. Lasts 24 hrs
Severe vomiting 
Cramps, nause
Non bloody diarrhea 
No fever
17
Q

S. aureus infections

A 
Aspiration pneumonia 
Osteomyelitis
Infective arthritis 
Acute endocarditis 
Bacteremia + sepsis 
Empyema
18
Q

Why is killing Staph difficult after phagocytic engulfment

A

They produce carotenoids and catalase – neutralize singlet oxygen and superoxide

19
Q

S. Epidermidis

Virulence factor and explain what it is

A

Glycocalyx: the exopolysaccharide slime. Helps in adhesion, antiphagocytic and makes it resistance to antibiotics

20
Q

S. Saparophyticus

A

Virulence related to binding to epithelium

UTI

  • dysuria
  • pyuria
  • organisms in urine
21
Q

What test differentiates between staphylococci from streptococci?

A

Catalase test is + in staphylococci

22
Q

The only one with Protein A

A

S. Aureus

PoD 2 (14 decks)

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